Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HHJ44_RS00665 Genome accession   NZ_CP053231
Coordinates   170589..171245 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SCU-306     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 165589..176245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHJ44_RS00635 (HHJ44_00635) dcyD 166468..167454 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  HHJ44_RS00640 (HHJ44_00640) tcyL 167469..168137 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HHJ44_RS00645 (HHJ44_00645) tcyN 168134..168886 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HHJ44_RS00650 (HHJ44_00650) sdiA 169116..169838 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  HHJ44_RS00655 (HHJ44_00655) yecF 169906..170130 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HHJ44_RS00660 (HHJ44_00660) yecU 170117..170293 (-) 177 WP_001307856.1 protein YecU -
  HHJ44_RS00665 (HHJ44_00665) letA 170589..171245 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HHJ44_RS00670 (HHJ44_00670) uvrC 171242..173074 (+) 1833 WP_128542902.1 excinuclease ABC subunit UvrC Machinery gene
  HHJ44_RS00675 (HHJ44_00675) pgsA 173131..173679 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HHJ44_RS00695 (HHJ44_00695) yecA 174329..174994 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=390715 HHJ44_RS00665 WP_000611328.1 170589..171245(+) (letA) [Escherichia coli strain SCU-306]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=390715 HHJ44_RS00665 WP_000611328.1 170589..171245(+) (letA) [Escherichia coli strain SCU-306]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482