Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   NLA_RS00095 Genome accession   NC_014752
Coordinates   20565..22073 (+) Length   502 a.a.
NCBI ID   WP_013448171.1    Uniprot ID   E4Z9R8
Organism   Neisseria lactamica 020-06     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 15565..27073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLA_RS00070 (NLA_0130) - 15825..16097 (-) 273 WP_042508097.1 spore cortex protein -
  NLA_RS00075 (NLA_0140) - 16296..17297 (+) 1002 WP_013448167.1 thiamine ABC transporter substrate-binding protein -
  NLA_RS00080 (NLA_0150) - 17392..18240 (+) 849 WP_042508098.1 mechanosensitive ion channel family protein -
  NLA_RS00085 - 18265..18750 (+) 486 WP_042508099.1 CinA family protein -
  NLA_RS00090 (NLA_0170) msrAB 18851..20419 (-) 1569 WP_013448170.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  NLA_RS00095 (NLA_0180) pilA 20565..22073 (+) 1509 WP_013448171.1 signal recognition particle-docking protein FtsY Machinery gene
  NLA_RS00100 (NLA_0190) - 22422..22691 (+) 270 WP_013448172.1 DUF3079 domain-containing protein -
  NLA_RS00105 (NLA_0200) yccS 23601..25751 (-) 2151 WP_013448173.1 YccS family putative transporter -
  NLA_RS00110 (NLA_0210) - 25842..27068 (-) 1227 WP_003711227.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 502 a.a.        Molecular weight: 53438.64 Da        Isoelectric Point: 4.3957

>NTDB_id=39047 NLA_RS00095 WP_013448171.1 20565..22073(+) (pilA) [Neisseria lactamica 020-06]
MFSFFRRKKKQETPAPEEAQIQETAVKAESEVAQIVENIKEDAESLTESVKGRVESAVETVSGAVEQVKETVAEMPSEAE
EAAEKAAEQVEAAKEAVAETVSGAVEQVKEAVAAMPSEAVEKAAECVESAKEAVVETVSKAVEQVQETVAAMPSEAGEAA
EKAAEQVEAAKEAVAETVSEAVEQVQEAVAEAVATTEEHKLSWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELE
TVLITGDMGMEATEYLMKDVRNRVSLKGLKDGNELRGALKDALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIG
KLAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLH
LMEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPIPVRYIG
VGEGIDDLRPFDARAFIDALLD

Nucleotide


Download         Length: 1509 bp        

>NTDB_id=39047 NLA_RS00095 WP_013448171.1 20565..22073(+) (pilA) [Neisseria lactamica 020-06]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACTCCGGCTCCAGAGGAGGCTCAAATTCAGGAAACCGCAGTAAA
AGCAGAATCTGAAGTTGCTCAAATAGTTGAAAATATTAAAGAAGATGCTGAATCTTTAACGGAAAGCGTCAAAGGGCGGG
TCGAATCTGCCGTTGAAACTGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGAG
GAAGCGGCTGAAAAAGCAGCGGAACAAGTCGAAGCGGCGAAAGAAGCCGTTGCCGAAACCGTCAGCGGTGCGGTTGAACA
AGTAAAGGAAGCTGTTGCCGCGATGCCGTCTGAAGCGGTTGAAAAAGCGGCGGAATGCGTTGAGTCCGCAAAAGAAGCAG
TCGTTGAAACCGTCAGCAAGGCTGTTGAGCAGGTTCAAGAAACCGTTGCCGCGATGCCGTCTGAAGCAGGGGAAGCGGCT
GAAAAAGCAGCGGAACAAGTCGAAGCGGCGAAAGAAGCCGTTGCCGAAACCGTCAGCGAGGCTGTCGAGCAAGTTCAAGA
AGCCGTTGCGGAAGCCGTTGCAACAACTGAAGAACACAAGCTCAGTTGGGCGGCACGTTTGAAACAAGGTTTGACCAAAT
CGCGCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTATACGAAGAGCTGGAA
ACCGTGCTGATTACCGGCGATATGGGTATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCAACCGCGTCAGCCTCAA
AGGGCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGATGCGCTGTACGACCTGATTAAGCCTCTGGAGAAACCGC
TGGTCTTGCCCGAAACCAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACTTCCATCGGC
AAACTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTGCTGCTTGCCGCAGGCGACACTTTCCGCGCAGCCGCGCGCGA
GCAGCTTCAGGCTTGGGGCGAGCGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCAGCCGTCTGCTTCG
ATGCCGTACAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTGGCCGACACCGCCGGCCGCCTGCCTACGCAGCTTCAT
TTGATGGAAGAAATCAAAAAAGTGAAGCGCGTGTTGCAAAAAGCTATGCCCGACGCGCCGCACGAAATCATCGTCGTCCT
CGATGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGCTTAATCGTAA
CCAAACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTCGCCTCCGACCGTCCTATCCCCGTCCGCTACATCGGC
GTGGGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTATTGACGCGCTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(217-283)

SRP54-type protein, GTPase domain (SRP54)

(302-501)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E4Z9R8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

85.167

83.267

0.709

Multiple sequence alignment