Detailed information NTG0390451

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HKM25_RS09965
• Genome accession: NZ_CP053210
• Coordinates: 1950438..1951337 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904870.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 6A-10
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1945438..1956337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKM25_RS09940 (HKM25_2037)	rsmA	1945768..1946640 (-)	873	WP_001216869.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
HKM25_RS09945 (HKM25_2038)	-	1946771..1947079 (-)	309	WP_000333257.1	hypothetical protein	-
HKM25_RS09950 (HKM25_2039)	-	1947072..1947713 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
HKM25_RS09955 (HKM25_2040)	-	1947715..1949745 (-)	2031	WP_000825260.1	bacteriocin-associated integral membrane family protein	-
HKM25_RS09960 (HKM25_2041)	-	1949822..1950118 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
HKM25_RS09965 (HKM25_2042)	comR	1950438..1951337 (-)	900	WP_000904870.1	helix-turn-helix transcriptional regulator	Regulator
HKM25_RS09970 (HKM25_2043)	rnmV	1951409..1951969 (-)	561	WP_000660019.1	ribonuclease M5	-
HKM25_RS09975 (HKM25_2044)	-	1951969..1952742 (-)	774	WP_000575598.1	TatD family hydrolase	-
HKM25_RS09980 (HKM25_2045)	-	1953047..1953766 (-)	720	WP_330777908.1	DUF1542 domain-containing protein	-
HKM25_RS09985 (HKM25_2046)	-	1953914..1954051 (-)	138	WP_000563000.1	hypothetical protein	-
HKM25_RS09990 (HKM25_2047)	rpmH	1954224..1954358 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
HKM25_RS09995 (HKM25_2048)	-	1954503..1955717 (-)	1215	WP_000666473.1	pyridoxal phosphate-dependent aminotransferase	-
HKM25_RS10000 (HKM25_2049)	-	1955873..1956166 (-)	294	WP_000977368.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35351.12 Da
• Isoelectric Point: 4.8336

>NTDB_id=390451 HKM25_RS09965 WP_000904870.1 1950438..1951337(-) (comR) [Streptococcus pneumoniae strain 6A-10]
MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=390451 HKM25_RS09965 WP_000904870.1 1950438..1951337(-) (comR) [Streptococcus pneumoniae strain 6A-10]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAGTTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAATTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361