Detailed information NTG0390367

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FSA40_RS04440
• Genome accession: NZ_CP044493
• Coordinates: 873201..874433 (+)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans strain MD
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 868201..879433

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA40_RS04415 (FSA40_0871)	-	869273..870448 (-)	1176	WP_002267988.1	hydroxymethylglutaryl-CoA synthase	-
FSA40_RS04420 (FSA40_0872)	-	870656..871495 (+)	840	WP_002264319.1	thymidylate synthase	-
FSA40_RS04425 (FSA40_0873)	pnuC	871612..872391 (+)	780	WP_002266473.1	nicotinamide riboside transporter PnuC	-
FSA40_RS04430 (FSA40_0874)	-	872476..872988 (+)	513	WP_002262814.1	dihydrofolate reductase	-
FSA40_RS04435 (FSA40_0875)	-	873006..873176 (+)	171	WP_002262815.1	hypothetical protein	-
FSA40_RS04440 (FSA40_0876)	clpX	873201..874433 (+)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FSA40_RS04445 (FSA40_0877)	yihA	874449..875042 (+)	594	WP_002262817.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FSA40_RS04450 (FSA40_0878)	-	875371..876747 (+)	1377	WP_002267986.1	amino acid permease	-
FSA40_RS04455 (FSA40_0879)	mmuM	876757..877707 (+)	951	WP_002264316.1	homocysteine S-methyltransferase	-
FSA40_RS04460 (FSA40_0880)	-	877841..879103 (-)	1263	WP_002263804.1	PLP-dependent aminotransferase family protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=390367 FSA40_RS04440 WP_002262816.1 873201..874433(+) (clpX) [Streptococcus mutans strain MD]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=390367 FSA40_RS04440 WP_002262816.1 873201..874433(+) (clpX) [Streptococcus mutans strain MD]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578