Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FSA40_RS02405 Genome accession   NZ_CP044493
Coordinates   452068..453369 (+) Length   433 a.a.
NCBI ID   WP_002266344.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 447068..458369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS02385 (FSA40_0469) - 448220..448888 (+) 669 WP_019314578.1 fructose-6-phosphate aldolase -
  FSA40_RS02390 (FSA40_0470) - 448927..450018 (+) 1092 WP_002280717.1 glycerol dehydrogenase -
  FSA40_RS02395 (FSA40_0471) cysK 450349..451275 (-) 927 WP_002269524.1 cysteine synthase A -
  FSA40_RS02400 (FSA40_0472) - 451366..451995 (-) 630 WP_002267042.1 YigZ family protein -
  FSA40_RS02405 (FSA40_0473) comFA/cflA 452068..453369 (+) 1302 WP_002266344.1 DEAD/DEAH box helicase Machinery gene
  FSA40_RS02410 (FSA40_0474) - 453366..454031 (+) 666 WP_002270131.1 ComF family protein -
  FSA40_RS02415 (FSA40_0475) raiA 454110..454658 (+) 549 WP_002263024.1 ribosome-associated translation inhibitor RaiA -
  FSA40_RS02420 (FSA40_0476) - 454782..455876 (+) 1095 WP_002273626.1 hypothetical protein -
  FSA40_RS02425 (FSA40_0477) - 455896..457596 (+) 1701 WP_151416196.1 zinc ribbon domain-containing protein -
  FSA40_RS02430 (FSA40_0478) - 457676..458311 (-) 636 WP_002263021.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49529.68 Da        Isoelectric Point: 9.9705

>NTDB_id=390356 FSA40_RS02405 WP_002266344.1 452068..453369(+) (comFA/cflA) [Streptococcus mutans strain MD]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRDKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=390356 FSA40_RS02405 WP_002266344.1 452068..453369(+) (comFA/cflA) [Streptococcus mutans strain MD]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAGACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGATAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACCTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.314

98.614

0.575
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

38.732

98.383

0.381

Multiple sequence alignment