Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FSA31_RS06815 Genome accession   NZ_CP044492
Coordinates   1388609..1389961 (-) Length   450 a.a.
NCBI ID   WP_002264821.1    Uniprot ID   A0AAX1K2Z0
Organism   Streptococcus mutans strain T8     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1383609..1394961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS06805 (FSA31_1349) rnc 1387007..1387702 (-) 696 WP_002266141.1 ribonuclease III -
  FSA31_RS06810 (FSA31_1350) vicX 1387809..1388612 (-) 804 WP_002284492.1 MBL fold metallo-hydrolase Regulator
  FSA31_RS06815 (FSA31_1351) vicK 1388609..1389961 (-) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FSA31_RS06820 (FSA31_1352) vicR 1389954..1390661 (-) 708 WP_002262930.1 response regulator YycF Regulator
  FSA31_RS06825 (FSA31_1353) - 1391014..1391796 (+) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  FSA31_RS06830 (FSA31_1354) - 1391793..1392605 (+) 813 WP_002275916.1 transporter substrate-binding domain-containing protein -
  FSA31_RS06835 (FSA31_1355) - 1392623..1393327 (+) 705 WP_002264823.1 amino acid ABC transporter permease -
  FSA31_RS06840 (FSA31_1356) - 1393342..1393992 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  FSA31_RS06845 (FSA31_1357) endA 1394060..1394941 (-) 882 WP_002264825.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51752.41 Da        Isoelectric Point: 4.4951

>NTDB_id=390304 FSA31_RS06815 WP_002264821.1 1388609..1389961(-) (vicK) [Streptococcus mutans strain T8]
MTNVFESSPLFLRILLAVLIILLFFYFIFLNYREYKNNNQVKQLNAKVRSLITGHYTDKLKVEDNSDLSELVNNVNDLSE
VFRLTHENLAQEKNRLTSILSYMTDGVLATDRRGKITVINDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTPEI
VLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIIRDYPDKSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKVTVTMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEDEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=390304 FSA31_RS06815 WP_002264821.1 1388609..1389961(-) (vicK) [Streptococcus mutans strain T8]
ATGACTAATGTGTTTGAATCAAGTCCCTTATTTTTACGAATTTTATTAGCAGTTTTAATCATTTTACTCTTTTTTTATTT
TATTTTTCTCAATTACAGAGAGTATAAAAATAATAATCAAGTTAAACAGTTAAATGCTAAAGTACGTTCTTTGATTACTG
GCCATTATACTGATAAATTAAAGGTTGAGGATAACTCTGACTTGTCAGAACTAGTGAATAACGTTAATGATTTATCAGAA
GTTTTCCGTTTAACGCATGAAAATTTGGCACAGGAGAAAAACCGTCTGACTAGTATTTTATCTTATATGACAGATGGTGT
TTTGGCAACAGATCGCCGCGGAAAGATTACCGTTATTAACGATATGGCGCAAAAGCAACTGAATGTAACGCGTGAGCAGG
CATTGGAGTGCAATATTCTGGATATTTTGGATGATGATAGTTATACTTACAATGATTTGATTACAAAAACGCCGGAAATT
GTTCTGACGCGGCGTGATGAATATGATGAATTTATCACTTTACGCATTCGTTTTGCCTTAAACCGCCGTGAAAGTGGCTT
TATTTCAGGACTAATTGCTGTCTTGCATGATGCGACCGAACAGGAAAAAGAAGAACGTGAACGCCGTCTCTTTGTTTCTA
ATGTCAGTCATGAACTGCGGACACCATTAACCTCTGTAAAGTCCTATTTAGAAGCTTTGGACGATGGTGCCCTGACAGAA
TCAGTGGCTCCTAGTTTTATCAAGGTATCACTTGATGAGACTAATCGCATGATGCGTATGATTACTGATTTACTTAGCTT
ATCACGTATTGATAATCAGACCAGTCATTTAGATGTTGAATTGACGAATTTTACAGCTTTTATGAATTATATTCTGGATC
GCTTTGATCAAATTCAAAGTCAGCAATCAACTAATAAGGTTTACGAAATTATTAGAGATTATCCTGACAAATCAGTTTGG
ATTGAAATTGATACCGATAAAATGACTCAGGTAATTGATAATATTTTAAATAATGCAATCAAATATTCACCTGATGGCGG
TAAGGTGACTGTAACGATGCAAACAACAGATACCCAACTCATCCTTTCTATATCCGACCAAGGCTTGGGTATTCCTAAGA
AGGATCTCCCTCTTATTTTTGACCGTTTTTATCGTGTTGATAAGGCAAGAAGCCGTGCTCAAGGTGGGACTGGTTTAGGA
TTAGCAATCGCCAAAGAAATTGTCAAACAGCATAAAGGCTTTATTTGGGCCAATAGTGAGGAAGGCGAAGGGTCGACCTT
TACCATCGTTTTACCTTATGAAAACGATAATGATGCAATTGATGAATGGGAAGAAGATGAAGACGAATCATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

99.556

100

0.996
  micB Streptococcus pneumoniae Cp1015

67.599

95.333

0.644

Multiple sequence alignment