Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FSA31_RS02395 Genome accession   NZ_CP044492
Coordinates   485241..486542 (+) Length   433 a.a.
NCBI ID   WP_002284360.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 480241..491542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS02375 (FSA31_0468) - 481390..482058 (+) 669 WP_002263030.1 fructose-6-phosphate aldolase -
  FSA31_RS02380 (FSA31_0469) - 482097..483188 (+) 1092 WP_002267044.1 glycerol dehydrogenase -
  FSA31_RS02385 (FSA31_0470) cysK 483522..484448 (-) 927 WP_151416609.1 cysteine synthase A -
  FSA31_RS02390 (FSA31_0471) - 484539..485168 (-) 630 WP_002263027.1 YigZ family protein -
  FSA31_RS02395 (FSA31_0472) comFA/cflA 485241..486542 (+) 1302 WP_002284360.1 DEAD/DEAH box helicase Machinery gene
  FSA31_RS02400 (FSA31_0473) - 486539..487204 (+) 666 WP_002267040.1 ComF family protein -
  FSA31_RS02405 (FSA31_0474) raiA 487283..487831 (+) 549 WP_002263024.1 ribosome-associated translation inhibitor RaiA -
  FSA31_RS02410 (FSA31_0475) - 487955..489049 (+) 1095 WP_002284361.1 hypothetical protein -
  FSA31_RS02415 (FSA31_0476) - 489069..490769 (+) 1701 WP_002284362.1 zinc ribbon domain-containing protein -
  FSA31_RS02420 (FSA31_0477) - 490849..491484 (-) 636 WP_002284363.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49559.71 Da        Isoelectric Point: 9.9705

>NTDB_id=390284 FSA31_RS02395 WP_002284360.1 485241..486542(+) (comFA/cflA) [Streptococcus mutans strain T8]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGTVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRDKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=390284 FSA31_RS02395 WP_002284360.1 485241..486542(+) (comFA/cflA) [Streptococcus mutans strain T8]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTACGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGATAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACTTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAGAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae D39

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae R6

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae TIGR4

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis NCTC 12261

58.548

98.614

0.577
  comFA/cflA Streptococcus mitis SK321

58.08

98.614

0.573
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

38.732

98.383

0.381

Multiple sequence alignment