Detailed information NTG0388816

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: F5989_RS02020
• Genome accession: NZ_CP044221
• Coordinates: 408294..409526 (-)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans strain NCH105
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 403294..414526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F5989_RS02000 (F5989_02035)	-	403624..404886 (+)	1263	WP_002281996.1	PLP-dependent aminotransferase family protein	-
F5989_RS02005 (F5989_02040)	mmuM	405020..405970 (-)	951	WP_002262819.1	homocysteine S-methyltransferase	-
F5989_RS02010 (F5989_02045)	-	405980..407356 (-)	1377	WP_002262818.1	amino acid permease	-
F5989_RS02015 (F5989_02050)	yihA	407685..408278 (-)	594	WP_002262817.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
F5989_RS02020 (F5989_02055)	clpX	408294..409526 (-)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
F5989_RS02025 (F5989_02060)	-	409551..409721 (-)	171	WP_002262815.1	hypothetical protein	-
F5989_RS02030 (F5989_02065)	-	409739..410251 (-)	513	WP_002271091.1	dihydrofolate reductase	-
F5989_RS02035 (F5989_02070)	pnuC	410336..411115 (-)	780	WP_002264318.1	nicotinamide riboside transporter PnuC	-
F5989_RS02040 (F5989_02075)	-	411232..412071 (-)	840	WP_002264319.1	thymidylate synthase	-
F5989_RS02045 (F5989_02080)	-	412279..413454 (+)	1176	WP_002273854.1	hydroxymethylglutaryl-CoA synthase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=388816 F5989_RS02020 WP_002262816.1 408294..409526(-) (clpX) [Streptococcus mutans strain NCH105]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=388816 F5989_RS02020 WP_002262816.1 408294..409526(-) (clpX) [Streptococcus mutans strain NCH105]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTATTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATC
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578