Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   FOB68_RS11340 Genome accession   NZ_CP044106
Coordinates   2228249..2229598 (+) Length   449 a.a.
NCBI ID   WP_000815640.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_660     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2220853..2238013 2228249..2229598 within 0


Gene organization within MGE regions


Location: 2220853..2238013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB68_RS11315 (FOB68_11320) - 2220853..2222316 (-) 1464 WP_001632592.1 hypothetical protein -
  FOB68_RS14640 - 2222481..2222723 (-) 243 WP_001632591.1 zinc ribbon domain-containing protein -
  FOB68_RS14540 - 2223025..2223174 (-) 150 WP_190349608.1 hypothetical protein -
  FOB68_RS11320 (FOB68_11325) - 2223174..2224688 (-) 1515 WP_000627204.1 protein kinase domain-containing protein -
  FOB68_RS11325 (FOB68_11330) - 2224706..2225773 (-) 1068 WP_001099283.1 hypothetical protein -
  FOB68_RS11330 (FOB68_11335) ssb 2225929..2226222 (+) 294 WP_000182688.1 cassette chromosome ssDNA-binding protein -
  FOB68_RS11335 (FOB68_11340) cch1 2226222..2228015 (+) 1794 WP_031928950.1 cassette chromosome replicative helicase -
  FOB68_RS11340 (FOB68_11345) ccrA 2228249..2229598 (+) 1350 WP_000815640.1 cassette chromosome recombinase CcrA Machinery gene
  FOB68_RS11345 (FOB68_11350) ccrB 2229620..2231248 (+) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  FOB68_RS11350 (FOB68_11355) - 2231770..2232120 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  FOB68_RS11360 (FOB68_11365) - 2232207..2232518 (+) 312 WP_000700851.1 DUF960 family protein -
  FOB68_RS11365 (FOB68_11370) - 2232533..2233039 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  FOB68_RS11370 (FOB68_11375) - 2233088..2234698 (+) 1611 Protein_2130 IS1182 family transposase -
  FOB68_RS11375 (FOB68_11380) - 2234689..2234931 (-) 243 Protein_2131 type I restriction enzyme endonuclease domain-containing protein -
  FOB68_RS11380 (FOB68_11385) - 2234921..2235907 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  FOB68_RS11385 (FOB68_11390) mecA 2236004..2238013 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52663.34 Da        Isoelectric Point: 9.9639

>NTDB_id=387937 FOB68_RS11340 WP_000815640.1 2228249..2229598(+) (ccrA) [Staphylococcus aureus strain FDAARGOS_660]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=387937 FOB68_RS11340 WP_000815640.1 2228249..2229598(+) (ccrA) [Staphylococcus aureus strain FDAARGOS_660]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(169-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.55

100

0.976
  ccrA Staphylococcus aureus COL

75.947

100

0.759

Multiple sequence alignment