Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HHJ23_RS10335 Genome accession   NZ_CP051738
Coordinates   2136178..2136834 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SCU-105     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2131178..2141834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHJ23_RS10305 (HHJ23_10310) dcyD 2132057..2133043 (+) 987 WP_001128229.1 D-cysteine desulfhydrase -
  HHJ23_RS10310 (HHJ23_10315) tcyL 2133058..2133726 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HHJ23_RS10315 (HHJ23_10320) tcyN 2133723..2134475 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HHJ23_RS10320 (HHJ23_10325) sdiA 2134705..2135427 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  HHJ23_RS10325 (HHJ23_10330) yecF 2135495..2135719 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HHJ23_RS10330 (HHJ23_10335) yecU 2135706..2135882 (-) 177 WP_000590347.1 protein YecU -
  HHJ23_RS10335 (HHJ23_10340) letA 2136178..2136834 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HHJ23_RS10340 (HHJ23_10345) uvrC 2136831..2138663 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HHJ23_RS10345 (HHJ23_10350) pgsA 2138720..2139268 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HHJ23_RS10365 (HHJ23_10370) - 2140261..2140542 (+) 282 WP_001303543.1 hypothetical protein -
  HHJ23_RS10370 (HHJ23_10375) - 2140731..2140871 (-) 141 WP_000078920.1 Hok/Gef family protein -
  HHJ23_RS10375 (HHJ23_10380) - 2141062..2141322 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=387756 HHJ23_RS10335 WP_000611328.1 2136178..2136834(+) (letA) [Escherichia coli strain SCU-105]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=387756 HHJ23_RS10335 WP_000611328.1 2136178..2136834(+) (letA) [Escherichia coli strain SCU-105]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment