Detailed information NTG0387734

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: FOB76_RS02885
• Genome accession: NZ_CP044093
• Coordinates: 538246..539316 (-)
• Length: 356 a.a.
• NCBI ID: WP_002986002.1
• Uniprot ID: Q1JNF7
• Organism: Streptococcus pyogenes strain FDAARGOS_668
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 533246..544316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB76_RS02875 (FOB76_02875)	-	537002..537181 (+)	180	WP_100215900.1	transposase	-
FOB76_RS09750	-	537208..537345 (+)	138	Protein_558	IS3 family transposase	-
FOB76_RS02880 (FOB76_02880)	amiF	537330..538253 (-)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
FOB76_RS02885 (FOB76_02885)	amiE	538246..539316 (-)	1071	WP_002986002.1	ABC transporter ATP-binding protein	Regulator
FOB76_RS02890 (FOB76_02890)	amiD	539325..540251 (-)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
FOB76_RS02895 (FOB76_02895)	amiC	540251..541753 (-)	1503	WP_002991105.1	ABC transporter permease	Regulator
FOB76_RS02900 (FOB76_02900)	amiA	541818..543788 (-)	1971	WP_024623426.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39749.85 Da
• Isoelectric Point: 5.7015

>NTDB_id=387734 FOB76_RS02885 WP_002986002.1 538246..539316(-) (amiE) [Streptococcus pyogenes strain FDAARGOS_668]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=387734 FOB76_RS02885 WP_002986002.1 538246..539316(-) (amiE) [Streptococcus pyogenes strain FDAARGOS_668]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGACAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: Q1JNF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.389	100	0.772
amiE	Streptococcus thermophilus LMG 18311	75.278	100	0.761
amiE	Streptococcus thermophilus LMD-9	75.278	100	0.761
oppD	Streptococcus mutans UA159	56.677	94.663	0.537