Detailed information NTG0387155

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FOB37_RS03745
• Genome accession: NZ_CP044047
• Coordinates: 357839..358639 (-)
• Length: 266 a.a.
• NCBI ID: WP_004191960.1
• Uniprot ID: A0AAJ5B1F9
• Organism: Klebsiella pneumoniae strain FDAARGOS_629
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 352839..363639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB37_RS03725 (FOB37_03725)	dksA	353419..353874 (-)	456	WP_002888845.1	RNA polymerase-binding protein DksA	-
FOB37_RS03730 (FOB37_03730)	sfsA	354037..354753 (-)	717	WP_002888848.1	DNA/RNA nuclease SfsA	-
FOB37_RS03735 (FOB37_03735)	thpR	354753..355289 (-)	537	WP_004177389.1	RNA 2',3'-cyclic phosphodiesterase	-
FOB37_RS03740 (FOB37_03740)	hrpB	355362..357791 (+)	2430	WP_064162458.1	ATP-dependent helicase HrpB	-
FOB37_RS03745 (FOB37_03745)	pilD	357839..358639 (-)	801	WP_004191960.1	prepilin peptidase	Machinery gene
FOB37_RS03750 (FOB37_03750)	-	358636..359382 (-)	747	WP_023282189.1	type II secretion system protein N	-
FOB37_RS03755 (FOB37_03755)	-	359372..359857 (-)	486	WP_004145896.1	type II secretion system protein M	-
FOB37_RS03760 (FOB37_03760)	gspL	359850..361043 (-)	1194	WP_004191957.1	type II secretion system protein GspL	-
FOB37_RS03765 (FOB37_03765)	gspK	361030..362016 (-)	987	WP_077265688.1	type II secretion system minor pseudopilin GspK	-
FOB37_RS03770 (FOB37_03770)	gspJ	362013..362609 (-)	597	WP_064162459.1	type II secretion system minor pseudopilin GspJ	-
FOB37_RS03775 (FOB37_03775)	gspI	362606..362971 (-)	366	WP_002889025.1	type II secretion system minor pseudopilin GspI	-
FOB37_RS03780 (FOB37_03780)	gspH	362968..363483 (-)	516	WP_062920974.1	type II secretion system minor pseudopilin GspH	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29403.04 Da
• Isoelectric Point: 8.8894

>NTDB_id=387155 FOB37_RS03745 WP_004191960.1 357839..358639(-) (pilD) [Klebsiella pneumoniae strain FDAARGOS_629]
MTTLAALSLHFPFVWYGFLLLFGLALGSFYNVVIYRLPRMLTQTADDERITLSTPGSSCPQCRQPIAWRDNIPLLSFLWL
GRRARCCQAPIAWSYPLTELATGLLFILAGALLAPGLPLAGGLVLLSFLLILARIDARTQLLPDRLTLPLLWAGLLFNLN
EVYIALPDAVAGAMAGYLALWSVYWLFRLLTGKEALGYGDFKLLAALGAWCGWQVLPQVLLLASASGLVWTLLQRLWTRQ
SLQQPLAFGPWLALAGGGIFLWQQMI

Nucleotide

• Length: 801 bp

>NTDB_id=387155 FOB37_RS03745 WP_004191960.1 357839..358639(-) (pilD) [Klebsiella pneumoniae strain FDAARGOS_629]
ATGACGACACTAGCCGCGTTATCGCTGCACTTTCCCTTTGTCTGGTATGGCTTTCTACTGCTGTTCGGCCTGGCGCTGGG
CAGCTTTTACAATGTGGTGATCTATCGTCTGCCGCGCATGTTGACCCAGACCGCGGACGACGAGCGGATAACCCTCAGCA
CCCCGGGCTCTTCCTGCCCGCAGTGCCGCCAGCCGATCGCCTGGCGGGACAATATCCCGCTGCTCAGTTTCCTCTGGCTG
GGCCGTCGCGCCCGCTGCTGTCAGGCGCCCATCGCGTGGAGCTATCCGCTGACCGAGCTGGCCACCGGCCTGCTGTTTAT
CCTCGCCGGAGCTTTGCTGGCGCCGGGCCTGCCGCTGGCGGGCGGCCTGGTGCTGCTCTCGTTCCTGCTGATACTGGCGC
GGATTGACGCCCGGACCCAGCTGCTGCCCGATCGCCTGACTCTGCCCCTGCTGTGGGCCGGGCTGCTGTTCAATCTTAAC
GAGGTGTACATTGCCCTGCCGGATGCGGTCGCCGGGGCGATGGCCGGTTATCTGGCGCTGTGGTCGGTCTACTGGCTGTT
CCGCCTGCTGACCGGGAAAGAGGCGCTGGGCTATGGCGATTTTAAGCTGCTGGCGGCGCTGGGCGCCTGGTGCGGCTGGC
AGGTTCTGCCGCAGGTGCTGTTGCTCGCTTCGGCCAGCGGGCTGGTGTGGACCCTACTGCAACGCCTGTGGACCCGGCAG
TCGCTGCAGCAGCCGCTGGCCTTCGGCCCCTGGCTGGCGCTGGCCGGCGGGGGTATTTTTCTCTGGCAGCAGATGATCTA
G

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (21-109)

• Type IV leader peptidase family (Peptidase_A24) (123-231)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.057	99.624	0.489
pilD	Vibrio campbellii strain DS40M4	46.545	100	0.481
pilD	Acinetobacter nosocomialis M2	46.388	98.872	0.459
pilD	Acinetobacter baumannii D1279779	45.627	98.872	0.451
pilD	Neisseria gonorrhoeae MS11	43.922	95.865	0.421