Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HHJ38_RS01755 Genome accession   NZ_CP051700
Coordinates   348495..349151 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SCU-125     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 343495..354151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHJ38_RS01725 (HHJ38_01725) dcyD 344374..345360 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  HHJ38_RS01730 (HHJ38_01730) tcyL 345375..346043 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HHJ38_RS01735 (HHJ38_01735) tcyN 346040..346792 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HHJ38_RS01740 (HHJ38_01740) sdiA 347022..347744 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  HHJ38_RS01745 (HHJ38_01745) yecF 347812..348036 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HHJ38_RS01750 (HHJ38_01750) yecU 348023..348199 (-) 177 WP_001307856.1 protein YecU -
  HHJ38_RS01755 (HHJ38_01755) letA 348495..349151 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HHJ38_RS01760 (HHJ38_01760) uvrC 349148..350980 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HHJ38_RS01765 (HHJ38_01765) pgsA 351037..351585 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HHJ38_RS01785 (HHJ38_01785) yecA 352234..352899 (+) 666 WP_000847886.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=386870 HHJ38_RS01755 WP_000611328.1 348495..349151(+) (letA) [Escherichia coli strain SCU-125]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=386870 HHJ38_RS01755 WP_000611328.1 348495..349151(+) (letA) [Escherichia coli strain SCU-125]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482