Detailed information NTG0386355

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: F0T10_RS08940
• Genome accession: NZ_CP043871
• Coordinates: 1715877..1716737 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain NG196
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1710877..1721737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F0T10_RS08925 (F0T10_09975)	dapD	1711387..1712208 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
F0T10_RS08930 (F0T10_09980)	pgi	1712418..1714061 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
F0T10_RS08935 (F0T10_09990)	pilG	1714571..1715803 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
F0T10_RS08940 (F0T10_09995)	pilD	1715877..1716737 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
F0T10_RS08945 (F0T10_10000)	coaE	1716734..1717366 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
F0T10_RS08950 (F0T10_10005)	-	1717359..1717568 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
F0T10_RS08955 (F0T10_10010)	pilF	1717654..1719330 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
F0T10_RS08965 (F0T10_10025)	-	1719668..1720114 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
F0T10_RS08970 (F0T10_10030)	-	1720118..1721092 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
F0T10_RS08980 (F0T10_10040)	rplU	1721316..1721624 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=386355 F0T10_RS08940 WP_003689814.1 1715877..1716737(+) (pilD) [Neisseria gonorrhoeae strain NG196]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=386355 F0T10_RS08940 WP_003689814.1 1715877..1716737(+) (pilD) [Neisseria gonorrhoeae strain NG196]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441