Detailed information
Bioinformatically predicted
Overview
| Name | pilL | Type | Machinery gene |
| Locus tag | F0T10_RS02335 | Genome accession | NZ_CP043871 |
| Coordinates | 450479..450952 (+) | Length | 157 a.a. |
| NCBI ID | WP_174813111.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain NG196 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 451498..501537 | 450479..450952 | flank | 546 |
Gene organization within MGE regions
Location: 450479..501537
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F0T10_RS02335 (F0T10_02640) | pilL | 450479..450952 (+) | 474 | WP_174813111.1 | PilX family type IV pilin | Machinery gene |
| F0T10_RS02340 (F0T10_02650) | - | 451564..452009 (-) | 446 | Protein_459 | AzlC family ABC transporter permease | - |
| F0T10_RS02345 (F0T10_02655) | dut | 452175..452627 (+) | 453 | WP_050303745.1 | dUTP diphosphatase | - |
| F0T10_RS02350 (F0T10_02660) | dapC | 452705..453892 (+) | 1188 | WP_164823235.1 | succinyldiaminopimelate transaminase | - |
| F0T10_RS02355 (F0T10_02665) | yaaA | 454203..454982 (+) | 780 | WP_003694987.1 | peroxide stress protein YaaA | - |
| F0T10_RS02370 (F0T10_02680) | - | 455513..456709 (+) | 1197 | WP_017147117.1 | tyrosine-type recombinase/integrase | - |
| F0T10_RS02375 (F0T10_02690) | - | 457065..457334 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| F0T10_RS02380 (F0T10_02695) | - | 457529..458212 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| F0T10_RS12980 | - | 458493..458759 (-) | 267 | Protein_466 | hypothetical protein | - |
| F0T10_RS02390 (F0T10_02705) | - | 458870..459085 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| F0T10_RS02395 (F0T10_02710) | - | 459137..459628 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| F0T10_RS02400 (F0T10_02715) | - | 459625..459807 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| F0T10_RS02405 (F0T10_02720) | - | 459947..460633 (-) | 687 | WP_082278088.1 | phage replication initiation protein, NGO0469 family | - |
| F0T10_RS02410 (F0T10_02725) | - | 460702..460863 (-) | 162 | WP_003693867.1 | hypothetical protein | - |
| F0T10_RS02415 (F0T10_02730) | - | 460860..461135 (-) | 276 | WP_047918704.1 | NGO1622 family putative holin | - |
| F0T10_RS02420 (F0T10_02735) | - | 461288..461620 (-) | 333 | WP_003695500.1 | hypothetical protein | - |
| F0T10_RS02425 (F0T10_02740) | - | 461761..462048 (-) | 288 | WP_050157611.1 | hypothetical protein | - |
| F0T10_RS02430 (F0T10_02745) | - | 462045..462521 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| F0T10_RS02435 (F0T10_02750) | - | 462554..462754 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| F0T10_RS02440 (F0T10_02755) | - | 463238..463456 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| F0T10_RS02445 (F0T10_02760) | - | 463473..463832 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| F0T10_RS02450 (F0T10_02765) | - | 463833..464372 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| F0T10_RS02455 (F0T10_02770) | - | 464532..465248 (-) | 717 | WP_003695999.1 | XRE family transcriptional regulator | - |
| F0T10_RS02460 (F0T10_02780) | - | 465629..465856 (+) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| F0T10_RS02465 (F0T10_02785) | - | 465853..466863 (+) | 1011 | WP_164823237.1 | helix-turn-helix domain-containing protein | - |
| F0T10_RS02470 (F0T10_02790) | - | 466877..467659 (+) | 783 | WP_033910919.1 | ATP-binding protein | - |
| F0T10_RS02475 (F0T10_02795) | - | 467672..467935 (+) | 264 | WP_174813108.1 | hypothetical protein | - |
| F0T10_RS02480 (F0T10_02800) | - | 467973..468467 (+) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| F0T10_RS02485 (F0T10_02805) | - | 468644..468793 (+) | 150 | WP_003692854.1 | hypothetical protein | - |
| F0T10_RS02490 (F0T10_02810) | - | 468886..469473 (+) | 588 | WP_134992956.1 | RusA family crossover junction endodeoxyribonuclease | - |
| F0T10_RS12825 | - | 469490..469618 (-) | 129 | WP_012503747.1 | hypothetical protein | - |
| F0T10_RS02495 (F0T10_02820) | - | 469740..470147 (+) | 408 | WP_047922557.1 | hypothetical protein | - |
| F0T10_RS02500 (F0T10_02825) | - | 470208..471167 (+) | 960 | WP_123768253.1 | hypothetical protein | - |
| F0T10_RS02505 (F0T10_02830) | - | 471458..472285 (+) | 828 | WP_050157519.1 | KilA-N domain-containing protein | - |
| F0T10_RS02510 (F0T10_02835) | - | 472578..473027 (+) | 450 | WP_003695485.1 | hypothetical protein | - |
| F0T10_RS02515 (F0T10_02840) | terL | 473089..474510 (+) | 1422 | WP_003697216.1 | phage terminase large subunit | - |
| F0T10_RS02520 (F0T10_02845) | - | 474507..476654 (+) | 2148 | WP_050157516.1 | phage portal protein | - |
| F0T10_RS02525 (F0T10_02850) | - | 476722..477879 (+) | 1158 | WP_050157513.1 | HK97 family phage prohead protease | - |
| F0T10_RS02530 (F0T10_02855) | - | 477920..479419 (+) | 1500 | WP_050157511.1 | hypothetical protein | - |
| F0T10_RS12000 (F0T10_02860) | - | 479426..479788 (+) | 363 | WP_003689082.1 | hypothetical protein | - |
| F0T10_RS02540 (F0T10_02865) | - | 479791..480321 (+) | 531 | WP_003689080.1 | head-tail connector protein | - |
| F0T10_RS02545 (F0T10_02870) | - | 480321..480803 (+) | 483 | WP_050157509.1 | HK97 gp10 family phage protein | - |
| F0T10_RS02550 (F0T10_02875) | - | 480800..481228 (+) | 429 | WP_003689076.1 | hypothetical protein | - |
| F0T10_RS02555 (F0T10_02880) | - | 481254..482027 (+) | 774 | WP_003691416.1 | hypothetical protein | - |
| F0T10_RS02560 (F0T10_02885) | - | 482088..482417 (+) | 330 | WP_003689072.1 | hypothetical protein | - |
| F0T10_RS02565 (F0T10_02890) | - | 482429..482695 (+) | 267 | WP_003689070.1 | hypothetical protein | - |
| F0T10_RS02570 (F0T10_02895) | - | 482695..483294 (+) | 600 | WP_003691415.1 | DUF2460 domain-containing protein | - |
| F0T10_RS02575 (F0T10_02900) | - | 483291..484145 (+) | 855 | WP_003698614.1 | DUF2163 domain-containing protein | - |
| F0T10_RS02580 (F0T10_02905) | - | 484147..484578 (+) | 432 | WP_003689064.1 | NlpC/P60 family protein | - |
| F0T10_RS02585 (F0T10_02910) | - | 484606..484884 (-) | 279 | WP_003689062.1 | helix-turn-helix domain-containing protein | - |
| F0T10_RS02590 (F0T10_02915) | - | 485124..489268 (+) | 4145 | Protein_508 | phage tail protein | - |
| F0T10_RS02595 (F0T10_02920) | - | 489380..489685 (+) | 306 | WP_003689058.1 | hypothetical protein | - |
| F0T10_RS02600 (F0T10_02925) | - | 489756..490226 (+) | 471 | WP_003689057.1 | hypothetical protein | - |
| F0T10_RS02605 (F0T10_02930) | - | 490227..490559 (+) | 333 | WP_003691408.1 | hypothetical protein | - |
| F0T10_RS02610 (F0T10_02935) | - | 490925..491272 (-) | 348 | WP_003689051.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| F0T10_RS02615 (F0T10_02940) | - | 491272..491508 (-) | 237 | WP_003689049.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| F0T10_RS12830 | - | 491548..491673 (+) | 126 | WP_255294325.1 | hypothetical protein | - |
| F0T10_RS02620 (F0T10_02950) | - | 491715..492254 (+) | 540 | WP_104691775.1 | TIGR02594 family protein | - |
| F0T10_RS02625 (F0T10_02955) | - | 492255..492599 (+) | 345 | WP_003695464.1 | hypothetical protein | - |
| F0T10_RS02630 | - | 492583..492756 (+) | 174 | WP_164823238.1 | hypothetical protein | - |
| F0T10_RS02635 (F0T10_02960) | - | 493068..493217 (+) | 150 | WP_003691402.1 | hypothetical protein | - |
| F0T10_RS02640 (F0T10_02965) | - | 493247..496294 (+) | 3048 | WP_050157602.1 | tape measure protein | - |
| F0T10_RS02645 (F0T10_02970) | - | 496354..496833 (-) | 480 | WP_002241413.1 | DUF4760 domain-containing protein | - |
| F0T10_RS02650 (F0T10_02980) | - | 497175..498164 (-) | 990 | WP_003689040.1 | tyrosine-type recombinase/integrase | - |
| F0T10_RS02655 (F0T10_02985) | - | 498424..498612 (-) | 189 | WP_003689039.1 | hypothetical protein | - |
| F0T10_RS02660 (F0T10_02990) | purM | 498853..499887 (+) | 1035 | WP_003691398.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| F0T10_RS02670 (F0T10_02995) | - | 500884..501537 (+) | 654 | WP_164823239.1 | IS1595 family transposase | - |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 17536.40 Da Isoelectric Point: 9.8238
>NTDB_id=386337 F0T10_RS02335 WP_174813111.1 450479..450952(+) (pilL) [Neisseria gonorrhoeae strain NG196]
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDNNQTIKSKLEIFVSGYKM
NPKIAKKYSVSVKFVDAEKPRVYRLVGVPNVGTGYTLSVWMNSVGDGYKCRDAASAKTYKEQLSGDGGCEALSNRKK
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDNNQTIKSKLEIFVSGYKM
NPKIAKKYSVSVKFVDAEKPRVYRLVGVPNVGTGYTLSVWMNSVGDGYKCRDAASAKTYKEQLSGDGGCEALSNRKK
Nucleotide
Download Length: 474 bp
>NTDB_id=386337 F0T10_RS02335 WP_174813111.1 450479..450952(+) (pilL) [Neisseria gonorrhoeae strain NG196]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACAATAATCAGACCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATGCGGAAAAACCAAGGGTATACAGGTTGGTCGG
TGTTCCGAACGTGGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCGGCAAAGACCTATAAAGAGCAGTTGTCCGGAGACGGTGGTTGTGAAGCCTTATCCAACCGTAAGAAATAG
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACAATAATCAGACCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATGCGGAAAAACCAAGGGTATACAGGTTGGTCGG
TGTTCCGAACGTGGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCGGCAAAGACCTATAAAGAGCAGTTGTCCGGAGACGGTGGTTGTGAAGCCTTATCCAACCGTAAGAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilL | Neisseria gonorrhoeae MS11 |
89.172 |
100 |
0.892 |
| pilX | Neisseria meningitidis 8013 |
85.35 |
100 |
0.854 |