Detailed information NTG0385975

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: F0T11_RS08895
• Genome accession: NZ_CP043816
• Coordinates: 1713335..1714195 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain NG251
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1708335..1719195

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F0T11_RS08880 (F0T11_09920)	dapD	1708845..1709666 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
F0T11_RS08885 (F0T11_09925)	pgi	1709876..1711519 (-)	1644	WP_003697594.1	glucose-6-phosphate isomerase	-
F0T11_RS08890 (F0T11_09930)	pilG	1712029..1713261 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
F0T11_RS08895 (F0T11_09935)	pilD	1713335..1714195 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
F0T11_RS08900 (F0T11_09940)	coaE	1714192..1714824 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
F0T11_RS08905 (F0T11_09945)	-	1714817..1715026 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
F0T11_RS08910 (F0T11_09950)	pilF	1715112..1716788 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
F0T11_RS08920 (F0T11_09965)	-	1717126..1717572 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
F0T11_RS08925 (F0T11_09970)	-	1717576..1718550 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
F0T11_RS08935 (F0T11_09980)	rplU	1718774..1719082 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=385975 F0T11_RS08895 WP_003689814.1 1713335..1714195(+) (pilD) [Neisseria gonorrhoeae strain NG251]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=385975 F0T11_RS08895 WP_003689814.1 1713335..1714195(+) (pilD) [Neisseria gonorrhoeae strain NG251]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441