Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HHM65_RS08270 Genome accession   NZ_CP051624
Coordinates   1662717..1663358 (-) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1657717..1668358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS08250 (HHM65_08255) - 1659091..1659729 (+) 639 WP_015057975.1 YigZ family protein -
  HHM65_RS08255 (HHM65_08260) cysK 1659833..1660768 (+) 936 WP_003062335.1 cysteine synthase A -
  HHM65_RS08260 (HHM65_08265) - 1660921..1661280 (-) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  HHM65_RS08265 (HHM65_08270) - 1661280..1662680 (-) 1401 WP_015057976.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  HHM65_RS08270 (HHM65_08275) vraR 1662717..1663358 (-) 642 WP_014612503.1 response regulator transcription factor Regulator
  HHM65_RS08275 (HHM65_08280) - 1663351..1664355 (-) 1005 WP_003061197.1 sensor histidine kinase -
  HHM65_RS08280 (HHM65_08285) liaF 1664352..1665044 (-) 693 WP_015057977.1 cell wall-active antibiotics response protein LiaF -
  HHM65_RS08285 (HHM65_08290) pknB 1665171..1667066 (-) 1896 WP_015057978.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HHM65_RS08290 (HHM65_08295) - 1667063..1667803 (-) 741 WP_003061786.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=385938 HHM65_RS08270 WP_014612503.1 1662717..1663358(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=385938 HHM65_RS08270 WP_014612503.1 1662717..1663358(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTGCTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGGGTTGAGGCGACTTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACCTCTTATTTGGACAATGAGAAAATTTACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGACCAACACCCCGATTTGCATGAAGAGCTAACCGCGCGCGAGTATGATATTTTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376