Detailed information NTG0385927

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: F0T12_RS08910
• Genome accession: NZ_CP043812
• Coordinates: 1717051..1717911 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain NG290
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1712051..1722911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F0T12_RS08895 (F0T12_09940)	dapD	1712561..1713382 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
F0T12_RS08900 (F0T12_09945)	pgi	1713592..1715235 (-)	1644	WP_003697594.1	glucose-6-phosphate isomerase	-
F0T12_RS08905 (F0T12_09950)	pilG	1715745..1716977 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
F0T12_RS08910 (F0T12_09955)	pilD	1717051..1717911 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
F0T12_RS08915 (F0T12_09960)	coaE	1717908..1718540 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
F0T12_RS08920 (F0T12_09965)	-	1718533..1718742 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
F0T12_RS08925 (F0T12_09970)	pilF	1718828..1720504 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
F0T12_RS08935 (F0T12_09985)	-	1720842..1721288 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
F0T12_RS08940 (F0T12_09990)	-	1721292..1722266 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
F0T12_RS08950 (F0T12_10000)	rplU	1722490..1722798 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=385927 F0T12_RS08910 WP_003689814.1 1717051..1717911(+) (pilD) [Neisseria gonorrhoeae strain NG290]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=385927 F0T12_RS08910 WP_003689814.1 1717051..1717911(+) (pilD) [Neisseria gonorrhoeae strain NG290]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441