Detailed information
Bioinformatically predicted
Overview
| Name | comH | Type | Machinery gene |
| Locus tag | HPPC_RS07230 | Genome accession | NC_014555 |
| Coordinates | 1495630..1497072 (-) | Length | 480 a.a. |
| NCBI ID | WP_000751640.1 | Uniprot ID | - |
| Organism | Helicobacter pylori PeCan4 | ||
| Function | import of DNA into the periplasm (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1496741..1562797 | 1495630..1497072 | flank | -331 |
Gene organization within MGE regions
Location: 1495630..1562797
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HPPC_RS07230 (HPPC_07480) | comH | 1495630..1497072 (-) | 1443 | WP_000751640.1 | hypothetical protein | Machinery gene |
| HPPC_RS07240 (HPPC_07485) | dnaA | 1497301..1498668 (-) | 1368 | WP_000380575.1 | chromosomal replication initiator protein DnaA | - |
| HPPC_RS07245 (HPPC_07490) | - | 1498820..1499356 (+) | 537 | WP_000922944.1 | purine-nucleoside phosphorylase | - |
| HPPC_RS07250 (HPPC_07495) | - | 1499403..1499642 (+) | 240 | WP_000461849.1 | DUF2443 family protein | - |
| HPPC_RS07255 (HPPC_07500) | glmS | 1499643..1501436 (+) | 1794 | WP_000334363.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
| HPPC_RS07260 (HPPC_07505) | thyX | 1501460..1502086 (+) | 627 | WP_000451936.1 | FAD-dependent thymidylate synthase | - |
| HPPC_RS08555 | - | 1502155..1502334 (+) | 180 | WP_001920240.1 | hypothetical protein | - |
| HPPC_RS07265 (HPPC_07515) | - | 1502416..1503615 (-) | 1200 | WP_000937091.1 | restriction endonuclease subunit S | - |
| HPPC_RS07270 (HPPC_07520) | - | 1503603..1504379 (-) | 777 | WP_000418238.1 | hypothetical protein | - |
| HPPC_RS07275 (HPPC_07525) | - | 1504467..1506929 (-) | 2463 | WP_000985409.1 | type I restriction-modification system subunit M | - |
| HPPC_RS07280 (HPPC_07530) | - | 1506999..1509974 (+) | 2976 | WP_000846152.1 | type I restriction endonuclease subunit R | - |
| HPPC_RS07285 (HPPC_07535) | - | 1509974..1510681 (+) | 708 | WP_000995276.1 | SprT family zinc-dependent metalloprotease | - |
| HPPC_RS07290 (HPPC_07540) | - | 1510771..1513329 (-) | 2559 | WP_324185949.1 | TonB-dependent receptor family protein | - |
| HPPC_RS07295 (HPPC_07545) | rocF | 1513816..1514784 (-) | 969 | WP_000604426.1 | arginase | - |
| HPPC_RS07300 (HPPC_07550) | - | 1514797..1516224 (-) | 1428 | WP_000654568.1 | amino acid permease | - |
| HPPC_RS07305 (HPPC_07555) | - | 1516418..1517560 (+) | 1143 | WP_000152063.1 | alanine dehydrogenase | - |
| HPPC_RS07310 | - | 1517683..1519364 (+) | 1682 | Protein_1423 | DUF262 domain-containing protein | - |
| HPPC_RS07315 (HPPC_07570) | - | 1519375..1520103 (-) | 729 | WP_000713173.1 | outer membrane protein | - |
| HPPC_RS07320 (HPPC_07575) | - | 1520287..1521141 (+) | 855 | WP_013356254.1 | NAD(+)/NADH kinase | - |
| HPPC_RS07325 (HPPC_07580) | - | 1521154..1522728 (+) | 1575 | WP_001204505.1 | DNA repair protein RecN | - |
| HPPC_RS07330 (HPPC_07585) | - | 1522725..1524032 (+) | 1308 | WP_000667867.1 | DUF814 domain-containing protein | - |
| HPPC_RS07335 (HPPC_07590) | - | 1524051..1524347 (+) | 297 | WP_000539103.1 | hypothetical protein | - |
| HPPC_RS07340 (HPPC_07595) | - | 1524672..1524938 (+) | 267 | WP_228841218.1 | hypothetical protein | - |
| HPPC_RS08435 (HPPC_07600) | - | 1525044..1525184 (+) | 141 | WP_013356255.1 | hypothetical protein | - |
| HPPC_RS07345 (HPPC_07605) | - | 1525210..1526073 (-) | 864 | WP_013356256.1 | 3'-5' exonuclease | - |
| HPPC_RS07350 (HPPC_07610) | rpe | 1526051..1526704 (-) | 654 | WP_000861445.1 | ribulose-phosphate 3-epimerase | - |
| HPPC_RS07355 (HPPC_07615) | - | 1526775..1527647 (+) | 873 | WP_000384761.1 | class 1 fructose-bisphosphatase | - |
| HPPC_RS07360 (HPPC_07620) | - | 1527647..1527850 (+) | 204 | WP_012443457.1 | hypothetical protein | - |
| HPPC_RS07365 (HPPC_07625) | - | 1527863..1528759 (+) | 897 | WP_000254491.1 | hypothetical protein | - |
| HPPC_RS07370 (HPPC_07630) | - | 1528752..1529483 (+) | 732 | WP_000891115.1 | hypothetical protein | - |
| HPPC_RS08660 | - | 1529672..1529791 (-) | 120 | Protein_1437 | DNA cytosine methyltransferase | - |
| HPPC_RS07380 | - | 1530930..1532985 (+) | 2056 | Protein_1438 | relaxase/mobilization nuclease domain-containing protein | - |
| HPPC_RS07385 (HPPC_07655) | - | 1534128..1535195 (+) | 1068 | WP_000933806.1 | tyrosine-type recombinase/integrase | - |
| HPPC_RS07390 (HPPC_07660) | - | 1535579..1536286 (-) | 708 | WP_001106879.1 | Fic family protein | - |
| HPPC_RS07395 (HPPC_07665) | - | 1536409..1536828 (-) | 420 | Protein_1441 | CAAX protease | - |
| HPPC_RS07400 (HPPC_07670) | - | 1537141..1537920 (+) | 780 | WP_001209224.1 | hypothetical protein | - |
| HPPC_RS07405 (HPPC_07675) | - | 1537940..1538233 (+) | 294 | WP_001160307.1 | hypothetical protein | - |
| HPPC_RS07410 (HPPC_07680) | - | 1538240..1539766 (+) | 1527 | WP_000323321.1 | hypothetical protein | - |
| HPPC_RS07415 (HPPC_07685) | - | 1539763..1540065 (+) | 303 | WP_001964151.1 | hypothetical protein | - |
| HPPC_RS07420 (HPPC_07690) | - | 1540066..1540332 (+) | 267 | WP_001173701.1 | hypothetical protein | - |
| HPPC_RS07425 (HPPC_07695) | - | 1540379..1542748 (+) | 2370 | WP_000657146.1 | VirB4 family type IV secretion/conjugal transfer ATPase | - |
| HPPC_RS07430 (HPPC_07700) | - | 1542751..1544784 (+) | 2034 | WP_000655390.1 | type IA DNA topoisomerase | - |
| HPPC_RS07435 (HPPC_07705) | - | 1544901..1546070 (+) | 1170 | WP_000044722.1 | type IV secretion system protein | - |
| HPPC_RS07440 (HPPC_07710) | - | 1546070..1547587 (+) | 1518 | WP_000714765.1 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| HPPC_RS07445 (HPPC_07715) | - | 1547587..1548852 (+) | 1266 | WP_000505567.1 | DNA type IV secretion system protein ComB10 | - |
| HPPC_RS07450 (HPPC_07720) | - | 1548922..1549215 (+) | 294 | WP_000395561.1 | hypothetical protein | - |
| HPPC_RS07455 (HPPC_07725) | - | 1549208..1549471 (+) | 264 | WP_000564638.1 | hypothetical protein | - |
| HPPC_RS07460 (HPPC_07730) | - | 1549468..1549767 (+) | 300 | WP_000660147.1 | hypothetical protein | - |
| HPPC_RS07465 (HPPC_07735) | - | 1549767..1550708 (+) | 942 | WP_000625143.1 | CpaF/VirB11 family protein | - |
| HPPC_RS07470 (HPPC_07740) | - | 1550705..1551160 (+) | 456 | WP_000795446.1 | hypothetical protein | - |
| HPPC_RS07475 (HPPC_07745) | - | 1551157..1551447 (+) | 291 | WP_000159813.1 | hypothetical protein | - |
| HPPC_RS07480 (HPPC_07750) | - | 1551448..1552005 (+) | 558 | WP_001167795.1 | hypothetical protein | - |
| HPPC_RS07485 (HPPC_07755) | - | 1552006..1553754 (+) | 1749 | WP_000570348.1 | type IV secretory system conjugative DNA transfer family protein | - |
| HPPC_RS07490 (HPPC_07760) | - | 1554266..1554547 (-) | 282 | WP_000921939.1 | type II toxin-antitoxin system YafQ family toxin | - |
| HPPC_RS07495 (HPPC_07765) | - | 1554540..1554854 (-) | 315 | WP_000073113.1 | hypothetical protein | - |
| HPPC_RS07500 (HPPC_07770) | - | 1555149..1557059 (+) | 1911 | WP_001162721.1 | relaxase/mobilization nuclease domain-containing protein | - |
| HPPC_RS07505 (HPPC_07775) | - | 1557084..1558256 (-) | 1173 | WP_000753635.1 | hypothetical protein | - |
| HPPC_RS07510 (HPPC_07780) | - | 1558300..1558584 (-) | 285 | WP_000394659.1 | hypothetical protein | - |
| HPPC_RS07515 (HPPC_07785) | - | 1558663..1559319 (-) | 657 | WP_000587383.1 | ParA family protein | - |
Sequence
Protein
Download Length: 480 a.a. Molecular weight: 54770.57 Da Isoelectric Point: 6.5117
>NTDB_id=38571 HPPC_RS07230 WP_000751640.1 1495630..1497072(-) (comH) [Helicobacter pylori PeCan4]
MKKTLCLSFFLTFSNPLQALVIELLEEIKTSPHKGTFKAKVLDSKEPKQVLGVYNISPHKKLTLTITHISTAIVYQPLDE
KLSLETTLNPNRPTIPRNTQIVFSSKELKEAHAHQMPSLNAPMQKPQNKPSSSQQPSQNFSYPEPKLGSKNSKNSLLQPL
VTPSKVSPANEVKTPTNDANPPLKHSSEDQENNLFITPPTEKTLPNNNTPNADIDENNESNENRDNVEKQAVRDANIKEF
ACGKWVYDDENLQAYRPSVLKRVDEDKQTATDITPCDYSNAENKSGKITTPYTKISVHKTEPLEEPQTFEAKNNFAILQA
RSSTEKCKRARARKDGTTRQCYLIEEPLKQAWESEYEITTQLVKAVYERPKQDDQVEPTFYETSELAYSSTRKSEITHNE
LNLNEKFMEFVEVYEGHYLNDIIKESSEYKEWVKNHVRFKEGVCMALEIEEQPRAKSTPLSIENSRVVCVKKGNYLFNEV
MKKTLCLSFFLTFSNPLQALVIELLEEIKTSPHKGTFKAKVLDSKEPKQVLGVYNISPHKKLTLTITHISTAIVYQPLDE
KLSLETTLNPNRPTIPRNTQIVFSSKELKEAHAHQMPSLNAPMQKPQNKPSSSQQPSQNFSYPEPKLGSKNSKNSLLQPL
VTPSKVSPANEVKTPTNDANPPLKHSSEDQENNLFITPPTEKTLPNNNTPNADIDENNESNENRDNVEKQAVRDANIKEF
ACGKWVYDDENLQAYRPSVLKRVDEDKQTATDITPCDYSNAENKSGKITTPYTKISVHKTEPLEEPQTFEAKNNFAILQA
RSSTEKCKRARARKDGTTRQCYLIEEPLKQAWESEYEITTQLVKAVYERPKQDDQVEPTFYETSELAYSSTRKSEITHNE
LNLNEKFMEFVEVYEGHYLNDIIKESSEYKEWVKNHVRFKEGVCMALEIEEQPRAKSTPLSIENSRVVCVKKGNYLFNEV
Nucleotide
Download Length: 1443 bp
>NTDB_id=38571 HPPC_RS07230 WP_000751640.1 1495630..1497072(-) (comH) [Helicobacter pylori PeCan4]
ATGAAAAAAACCCTTTGTCTGTCTTTCTTTCTGACTTTCTCTAACCCTCTTCAAGCCCTTGTGATCGAGCTTTTAGAAGA
AATCAAAACTTCCCCGCATAAAGGCACTTTTAAGGCTAAAGTCCTTGATTCTAAAGAACCCAAACAGGTTTTAGGCGTTT
ATAATATCTCCCCACACAAAAAACTCACGCTCACAATCACTCACATATCTACTGCAATTGTTTATCAACCCCTTGATGAA
AAACTTTCTTTAGAAACGACCTTAAACCCTAACCGCCCTACTATCCCTAGAAACACCCAAATTGTTTTTTCTTCAAAAGA
ATTGAAAGAAGCGCACGCGCACCAAATGCCTTCTTTAAATGCACCCATGCAAAAACCACAAAATAAACCCAGCTCATCGC
AACAACCTTCTCAAAACTTTTCTTACCCAGAGCCCAAACTAGGCTCTAAAAACTCTAAAAACAGCCTTTTACAGCCTTTA
GTAACTCCCAGCAAAGTAAGCCCTGCTAATGAAGTTAAAACGCCAACAAACGACGCTAATCCCCCTTTAAAACATTCTTC
AGAAGATCAAGAAAACAACCTCTTTATAACGCCACCCACTGAAAAAACGCTCCCTAATAACAACACCCCTAACGCTGATA
TTGATGAAAACAATGAAAGCAACGAAAATAGGGACAATGTGGAAAAACAAGCCGTTAGAGATGCTAATATTAAAGAATTT
GCATGCGGGAAGTGGGTTTATGACGATGAAAATTTACAAGCCTATCGCCCAAGCGTTTTAAAACGCGTTGATGAAGACAA
ACAAACTGCGACAGATATTACCCCTTGCGATTACAGCAACGCTGAAAATAAAAGCGGTAAAATCACTACCCCCTATACTA
AAATCTCTGTCCATAAAACAGAGCCTTTAGAAGAGCCACAAACTTTTGAAGCTAAAAATAATTTCGCCATTCTTCAAGCC
AGAAGCTCTACAGAAAAATGCAAAAGGGCTAGAGCAAGAAAAGACGGCACGACTAGGCAATGCTATCTGATAGAAGAGCC
TTTAAAACAAGCGTGGGAAAGCGAGTATGAAATCACCACGCAATTAGTAAAAGCCGTATATGAGCGCCCCAAACAAGACG
ATCAAGTAGAGCCGACTTTTTATGAAACCAGCGAATTGGCTTATTCTTCCACACGAAAAAGCGAAATAACGCATAATGAA
TTGAATTTGAATGAAAAATTCATGGAATTTGTGGAAGTGTATGAGGGGCATTATTTAAACGATATAATCAAAGAGAGCAG
TGAATACAAAGAATGGGTTAAAAACCATGTGCGCTTTAAAGAAGGGGTGTGCATGGCCTTAGAAATAGAAGAGCAACCAC
GAGCTAAAAGCACGCCTTTGAGCATTGAAAACTCTCGTGTGGTGTGTGTCAAAAAGGGGAATTATTTATTCAACGAAGTT
TAA
ATGAAAAAAACCCTTTGTCTGTCTTTCTTTCTGACTTTCTCTAACCCTCTTCAAGCCCTTGTGATCGAGCTTTTAGAAGA
AATCAAAACTTCCCCGCATAAAGGCACTTTTAAGGCTAAAGTCCTTGATTCTAAAGAACCCAAACAGGTTTTAGGCGTTT
ATAATATCTCCCCACACAAAAAACTCACGCTCACAATCACTCACATATCTACTGCAATTGTTTATCAACCCCTTGATGAA
AAACTTTCTTTAGAAACGACCTTAAACCCTAACCGCCCTACTATCCCTAGAAACACCCAAATTGTTTTTTCTTCAAAAGA
ATTGAAAGAAGCGCACGCGCACCAAATGCCTTCTTTAAATGCACCCATGCAAAAACCACAAAATAAACCCAGCTCATCGC
AACAACCTTCTCAAAACTTTTCTTACCCAGAGCCCAAACTAGGCTCTAAAAACTCTAAAAACAGCCTTTTACAGCCTTTA
GTAACTCCCAGCAAAGTAAGCCCTGCTAATGAAGTTAAAACGCCAACAAACGACGCTAATCCCCCTTTAAAACATTCTTC
AGAAGATCAAGAAAACAACCTCTTTATAACGCCACCCACTGAAAAAACGCTCCCTAATAACAACACCCCTAACGCTGATA
TTGATGAAAACAATGAAAGCAACGAAAATAGGGACAATGTGGAAAAACAAGCCGTTAGAGATGCTAATATTAAAGAATTT
GCATGCGGGAAGTGGGTTTATGACGATGAAAATTTACAAGCCTATCGCCCAAGCGTTTTAAAACGCGTTGATGAAGACAA
ACAAACTGCGACAGATATTACCCCTTGCGATTACAGCAACGCTGAAAATAAAAGCGGTAAAATCACTACCCCCTATACTA
AAATCTCTGTCCATAAAACAGAGCCTTTAGAAGAGCCACAAACTTTTGAAGCTAAAAATAATTTCGCCATTCTTCAAGCC
AGAAGCTCTACAGAAAAATGCAAAAGGGCTAGAGCAAGAAAAGACGGCACGACTAGGCAATGCTATCTGATAGAAGAGCC
TTTAAAACAAGCGTGGGAAAGCGAGTATGAAATCACCACGCAATTAGTAAAAGCCGTATATGAGCGCCCCAAACAAGACG
ATCAAGTAGAGCCGACTTTTTATGAAACCAGCGAATTGGCTTATTCTTCCACACGAAAAAGCGAAATAACGCATAATGAA
TTGAATTTGAATGAAAAATTCATGGAATTTGTGGAAGTGTATGAGGGGCATTATTTAAACGATATAATCAAAGAGAGCAG
TGAATACAAAGAATGGGTTAAAAACCATGTGCGCTTTAAAGAAGGGGTGTGCATGGCCTTAGAAATAGAAGAGCAACCAC
GAGCTAAAAGCACGCCTTTGAGCATTGAAAACTCTCGTGTGGTGTGTGTCAAAAAGGGGAATTATTTATTCAACGAAGTT
TAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comH | Helicobacter pylori 26695 |
95 |
100 |
0.95 |