Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPPC_RS00105 Genome accession   NC_014555
Coordinates   14036..16399 (+) Length   787 a.a.
NCBI ID   WP_000890521.1    Uniprot ID   -
Organism   Helicobacter pylori PeCan4     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9036..21399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPPC_RS00075 (HPPC_00055) groES 9047..9409 (-) 363 WP_000671960.1 co-chaperone GroES -
  HPPC_RS00080 (HPPC_00060) dnaG 9696..11375 (+) 1680 WP_000601568.1 DNA primase -
  HPPC_RS00085 (HPPC_00065) - 11372..12424 (+) 1053 WP_000721170.1 MnmA/TRMU family protein -
  HPPC_RS00090 (HPPC_00070) - 12517..13344 (+) 828 WP_001154916.1 DUF5718 family protein -
  HPPC_RS00095 (HPPC_00075) comB2 13490..13771 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HPPC_RS00100 (HPPC_00080) comB3 13771..14034 (+) 264 WP_000584974.1 hypothetical protein Machinery gene
  HPPC_RS00105 (HPPC_00085) comB4 14036..16399 (+) 2364 WP_000890521.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPPC_RS00110 (HPPC_00090) - 16704..18044 (+) 1341 WP_013356091.1 COG3014 family protein -
  HPPC_RS00115 (HPPC_00095) cheV1 18139..19104 (+) 966 WP_000785465.1 chemotaxis protein CheV1 -
  HPPC_RS00120 (HPPC_00100) nspC 19101..20321 (+) 1221 WP_000760840.1 carboxynorspermidine decarboxylase -
  HPPC_RS00125 (HPPC_00105) lpxE 20331..20864 (-) 534 WP_228841221.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90218.75 Da        Isoelectric Point: 8.8674

>NTDB_id=38554 HPPC_RS00105 WP_000890521.1 14036..16399(+) (comB4) [Helicobacter pylori PeCan4]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVVRIVVKRRKIDHQQSIQSDSKYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSTTFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSHLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIYLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEVARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLSLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNAKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=38554 HPPC_RS00105 WP_000890521.1 14036..16399(+) (comB4) [Helicobacter pylori PeCan4]
ATGTTAGAAAAGCTTTTGAGCGCTATCAAACAAAAGGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACTGAGCGCCAGATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGTGCGAATCGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAGCATTCAATCTGACTCTAA
ATACTTGCAAGCGATCTTGAACCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTACAAGGTGTTTTGGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGACATCCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCTTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTACCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAACCAAAAAACCTACAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAAACGCC
TTTAGATATTATCTTTTCCATAGAGCCTATGAGCGCGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTCATCTTGTTAAAAACGAGCTGCTAGAATACCAAGAACTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACCAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATTTATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAGTCGCTAGAGTGAATGGGCATACTCTAATCATAGGGGCTACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCACGACGGCAAATCTTTTAGCATTAATCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCTTTTAGTTTGCTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTAAGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACTTAGACACTATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACGCTAAAATTAACGCTTTAATCACGCAAGCTAGAAAGGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAATTGAGCGGGGTTAAAAACGCTCATAGTTTTTTGAGCAACATGGGGA
CTCTTATTTTGTACCCGCAAAAAAACGCTAGGGAGTTGAAACACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAATTCTAACATGATTGATGT
GAGTTTGGAGGGTTTGGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.205

100

0.972

Multiple sequence alignment