Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   MGAS2221_RS02410 Genome accession   NZ_CP043530
Coordinates   453804..454613 (+) Length   269 a.a.
NCBI ID   WP_002985641.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS2221     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 448804..459613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS2221_RS02390 (MGAS2221_0477) - 449246..450493 (+) 1248 WP_010921989.1 AMP-binding protein -
  MGAS2221_RS02395 (MGAS2221_0478) - 450549..451583 (+) 1035 WP_011285430.1 DUF3114 domain-containing protein -
  MGAS2221_RS02400 (MGAS2221_0479) vicR 451745..452455 (+) 711 WP_002985645.1 response regulator YycF Regulator
  MGAS2221_RS02405 (MGAS2221_0480) vicK 452448..453800 (+) 1353 WP_002995609.1 cell wall metabolism sensor histidine kinase VicK Regulator
  MGAS2221_RS02410 (MGAS2221_0481) vicX 453804..454613 (+) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  MGAS2221_RS02415 (MGAS2221_0482) rnc 455057..455749 (+) 693 WP_002990670.1 ribonuclease III -
  MGAS2221_RS02420 (MGAS2221_0483) smc 455750..459289 (+) 3540 WP_010921991.1 chromosome segregation protein SMC -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 30095.20 Da        Isoelectric Point: 5.5314

>NTDB_id=384835 MGAS2221_RS02410 WP_002985641.1 453804..454613(+) (vicX) [Streptococcus pyogenes strain MGAS2221]
MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLLAEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLD
IYANEKTWQLMDECNMLGKLDASQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKKIYLGHLSKENNIKELAHMTMVN
QLAMADLAVGTDFTVHDTSPDTACPLTDI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=384835 MGAS2221_RS02410 WP_002985641.1 453804..454613(+) (vicX) [Streptococcus pyogenes strain MGAS2221]
ATGAATGAGAGTGGTTTTAAATACAGTATTTTAGCATCTGGGTCCACAGGAAATTGTTTTTATTTAGAAACACCTAAAAA
ACGCTTATTGATTGATGCAGGGCTTACTGGTAAGAAAATTACCAGTCTTCTTGCTGAAATTGACCGCAAACCTGAGGATT
TGGATGCTATTTTGATTACCCATGAGCACTCTGACCATATTAAGGGTGTAGGCGTTATGGCCCGCAAATACCATTTGGAT
ATCTATGCTAATGAAAAAACATGGCAGCTGATGGATGAGTGCAATATGCTAGGTAAGCTTGATGCCTCACAAAAACATAT
TTTCCAAAGGGATAAAGTTTTGACCTTTGGAGATGTTGATATCGAAAGTTTTGGAGTCAGCCATGACGCTATTGATCCTC
AATTTTATCGGATTATGAAAGATAATAAGTCTTTTGTGATGTTGACAGATACAGGATATGTCAGTGATAGGATGACAGGT
ATTATTGAAAATGCAGATGGCTACTTGATTGAATCCAATCATGATATTGAAATTTTGAGATCAGGCTCTTATCCTTGGAG
CTTAAAGCAGCGTATTTTATCTGATTTAGGACATTTATCAAATGAAGATGGAGCGGGAGCCATGATTAGAAGCCTGGGGT
ACAATACCAAAAAAATATACCTAGGTCATCTGAGTAAAGAAAATAACATCAAAGAGTTAGCGCATATGACGATGGTCAAT
CAACTGGCTATGGCAGATTTAGCAGTAGGTACAGACTTTACGGTCCATGATACCTCTCCAGATACTGCTTGTCCATTAAC
TGATATTTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

75.836

100

0.758

Multiple sequence alignment