Detailed information NTG0383596

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FY406_RS08420
• Genome accession: NZ_CP043405
• Coordinates: 1682143..1683372 (+)
• Length: 409 a.a.
• NCBI ID: WP_003088137.1
• Uniprot ID: A0A7X9LBX9
• Organism: Streptococcus ratti strain ATCC 31377
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1677143..1688372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FY406_RS08395 (FY406_08395)	-	1678214..1679386 (-)	1173	WP_003088127.1	hydroxymethylglutaryl-CoA synthase	-
FY406_RS08400 (FY406_08400)	-	1679590..1680429 (+)	840	WP_003088129.1	thymidylate synthase	-
FY406_RS08405 (FY406_08405)	pnuC	1680546..1681319 (+)	774	WP_050990613.1	nicotinamide riboside transporter PnuC	-
FY406_RS08410 (FY406_08410)	-	1681428..1681925 (+)	498	WP_003088134.1	dihydrofolate reductase	-
FY406_RS08420 (FY406_08420)	clpX	1682143..1683372 (+)	1230	WP_003088137.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FY406_RS08425 (FY406_08425)	yihA	1683379..1683975 (+)	597	WP_281347398.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FY406_RS08430 (FY406_08430)	-	1684261..1685637 (+)	1377	WP_003088141.1	amino acid permease	-
FY406_RS08435 (FY406_08435)	mmuM	1685647..1686603 (+)	957	WP_003088142.1	homocysteine S-methyltransferase	-
FY406_RS08440 (FY406_08440)	-	1686751..1688016 (-)	1266	WP_003088143.1	PLP-dependent aminotransferase family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45169.63 Da
• Isoelectric Point: 4.4401

>NTDB_id=383596 FY406_RS08420 WP_003088137.1 1682143..1683372(+) (clpX) [Streptococcus ratti strain ATCC 31377]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLSDLTEVPKPKELLEILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQEDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKVDDKSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYKTLLSYDGVELEFDQDALEAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKEAVEG
TDKPILETA

Nucleotide

• Length: 1230 bp

>NTDB_id=383596 FY406_RS08420 WP_003088137.1 1682143..1683372(+) (clpX) [Streptococcus ratti strain ATCC 31377]
ATGGCTGGAAATAGAACGAATGATGTCACAGTTCACTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATCAT
TGCAGGCAACGGTGTGTTCATCTGCAATGAATGTGTTGAATTATCTCAGGAAATCATCCGCGAAGAGTTAGCAGAAGAAG
TTTTGTCTGATCTCACTGAAGTACCAAAACCTAAGGAACTCTTGGAAATTTTGGACAGCTATGTAATCGGGCAGGATCGT
GCTAAACGTGCCTTGGCTGTTGCAGTTTATAACCATTATAAACGCATCAGTTTCACAGAAAGTCAGGAAGATCAGGATGT
TGACTTACAAAAGTCTAACATTCTCATGATTGGCCCGACAGGTTCCGGAAAAACTTTTTTGGCTCAGACCTTGGCTAAAA
GTCTCAATGTTCCCTTTGCTATTGCAGATGCCACTGCCCTAACTGAAGCTGGTTATGTGGGAGAAGATGTTGAAAATATT
CTGCTGAAGCTAATTCAGGCCGCTGATTATAATGTGGAGCGCGCGGAGCGCGGCATTATCTATGTCGATGAAATTGACAA
GATCGCTAAAAAAGGTGAAAATGTTTCAATTACCCGTGATGTTTCCGGTGAGGGTGTTCAGCAGGCCCTGCTTAAAATTA
TTGAAGGAACAGTAGCCAGTGTACCGCCGCAAGGTGGCCGCAAGCATCCGCAGCAGGAAATGATTCAGATCAATACCAAG
AATATTCTTTTTATCGTTGGCGGTGCTTTTGACGGAATCGAAGATATTGTTAAGCAGCGCTTGGGAGAAAAGATTATCGG
TTTCGGACAAAATAATAAAAAGGTTGATGACAAGTCATCCTACATGCAAGAGATTATTTCTGAGGATATTCAAAAATTCG
GTCTGATTCCCGAGTTTATCGGTCGCCTGCCGGTCTTGGCAGCCCTTGAACAGCTGACAGTTGACGATTTGGTTAAGATT
CTGACAGAGCCTAAGAATGCCTTGGTTAAGCAGTATAAGACTCTTCTGTCTTATGACGGTGTTGAGCTCGAATTTGATCA
AGATGCTCTGGAAGCTATTGCTCAAAAGGCGATTGAGCGGAAAACAGGTGCACGGGGACTTCGGTCTATTATTGAAGAAA
CCATGCTGGACTTGATGTTTGAAATTCCAAGCCAGGAAGATGTGACCTGTGTTCGCATTACCAAAGAAGCTGTTGAAGGA
ACAGATAAACCGATTCTTGAAACGGCCTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

3D structure

• AlphaFold DB: A0A7X9LBX9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	97.311	100	0.973
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	98.044	0.579