Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HGG68_RS10660 Genome accession   NZ_CP051263
Coordinates   2154113..2154769 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli CFT073     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2149113..2159769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HGG68_RS10630 yecA 2150365..2151030 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  HGG68_RS10650 pgsA 2151679..2152227 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HGG68_RS10655 uvrC 2152284..2154116 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HGG68_RS10660 letA 2154113..2154769 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HGG68_RS10665 yecU 2155065..2155241 (+) 177 WP_001304283.1 protein YecU -
  HGG68_RS10670 yecF 2155228..2155452 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  HGG68_RS10675 sdiA 2155520..2156242 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  HGG68_RS10680 tcyN 2156472..2157224 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HGG68_RS10685 tcyL 2157221..2157889 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  HGG68_RS10690 dcyD 2157904..2158890 (-) 987 WP_001128236.1 D-cysteine desulfhydrase -
  HGG68_RS10695 tnpA 2159058..2159516 (-) 459 WP_000526115.1 IS200/IS605-like element IS200C family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=383390 HGG68_RS10660 WP_000611328.1 2154113..2154769(-) (letA) [Escherichia coli CFT073]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=383390 HGG68_RS10660 WP_000611328.1 2154113..2154769(-) (letA) [Escherichia coli CFT073]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482