Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HF562_RS09900 Genome accession   NZ_CP051222
Coordinates   2049329..2049985 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SCZE5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2044329..2054985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HF562_RS09870 (HF562_09880) dcyD 2045208..2046194 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HF562_RS09875 (HF562_09885) tcyL 2046209..2046877 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  HF562_RS09880 (HF562_09890) tcyN 2046874..2047626 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HF562_RS09885 (HF562_09895) sdiA 2047856..2048578 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  HF562_RS09890 (HF562_09900) yecF 2048646..2048870 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HF562_RS09895 (HF562_09905) yecU 2048857..2049033 (-) 177 WP_000590344.1 protein YecU -
  HF562_RS25530 - 2049071..2049187 (-) 117 WP_001302039.1 hypothetical protein -
  HF562_RS09900 (HF562_09910) letA 2049329..2049985 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HF562_RS09905 (HF562_09915) uvrC 2049982..2051814 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  HF562_RS09910 (HF562_09920) pgsA 2051871..2052419 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HF562_RS09930 (HF562_09940) yecA 2053068..2053733 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=383323 HF562_RS09900 WP_000611328.1 2049329..2049985(+) (letA) [Escherichia coli strain SCZE5]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=383323 HF562_RS09900 WP_000611328.1 2049329..2049985(+) (letA) [Escherichia coli strain SCZE5]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482