Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   SP670_RS10750 Genome accession   NC_014498
Coordinates   1986299..1987252 (-) Length   317 a.a.
NCBI ID   WP_000345085.1    Uniprot ID   A0A0T9IPY8
Organism   Streptococcus pneumoniae 670-6B     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1981299..1992252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP670_RS10725 (SP670_2119) - 1982061..1982684 (-) 624 WP_000932659.1 hypothetical protein -
  SP670_RS10730 (SP670_2120) jag 1982735..1983721 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  SP670_RS10735 (SP670_2121) - 1983740..1984564 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  SP670_RS10740 (SP670_2122) rnpA 1984539..1984910 (-) 372 WP_000739241.1 ribonuclease P protein component -
  SP670_RS10745 (SP670_2123) - 1985058..1986248 (-) 1191 WP_000167766.1 acetate kinase -
  SP670_RS10750 (SP670_2124) comYH 1986299..1987252 (-) 954 WP_000345085.1 class I SAM-dependent methyltransferase Machinery gene
  SP670_RS13660 - 1987313..1987900 (-) 588 Protein_2022 class I SAM-dependent methyltransferase -
  SP670_RS10765 (SP670_2127) comGG/cglG 1988037..1988450 (-) 414 WP_000265619.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP670_RS10770 (SP670_2128) comGF/cglF 1988428..1988889 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  SP670_RS10775 (SP670_2129) comGE/cglE 1988852..1989154 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SP670_RS10780 (SP670_2130) comGD/cglD 1989117..1989521 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  SP670_RS10785 (SP670_2131) comGC/cglC 1989514..1989780 (-) 267 WP_000962026.1 competence type IV pilus major pilin ComGC Machinery gene
  SP670_RS10790 (SP670_2132) - 1989782..1990039 (-) 258 WP_000698513.1 hypothetical protein -
  SP670_RS10795 (SP670_2133) - 1990271..1991227 (-) 957 WP_000350474.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SP670_RS10800 (SP670_2134) - 1991227..1991562 (-) 336 WP_001186218.1 phage holin -
  SP670_RS10805 (SP670_2135) - 1991566..1991865 (-) 300 WP_001811580.1 hypothetical protein -
  SP670_RS10810 (SP670_2136) - 1991874..1992224 (-) 351 WP_000852245.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35703.88 Da        Isoelectric Point: 4.2270

>NTDB_id=38323 SP670_RS10750 WP_000345085.1 1986299..1987252(-) (comYH) [Streptococcus pneumoniae 670-6B]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=38323 SP670_RS10750 WP_000345085.1 1986299..1987252(-) (comYH) [Streptococcus pneumoniae 670-6B]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T9IPY8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment