Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HF575_RS16195 Genome accession   NZ_CP051158
Coordinates   3451482..3452138 (+) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain 17MR471     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3446482..3457138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HF575_RS16165 (HF575_16205) dcyD 3447361..3448347 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HF575_RS16170 (HF575_16210) tcyL 3448362..3449030 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HF575_RS16175 (HF575_16215) tcyN 3449027..3449779 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HF575_RS16180 (HF575_16220) sdiA 3450009..3450731 (+) 723 WP_032266073.1 transcriptional regulator SdiA -
  HF575_RS16185 (HF575_16225) yecF 3450799..3451023 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HF575_RS16190 (HF575_16230) yecU 3451010..3451186 (-) 177 WP_001307856.1 protein YecU -
  HF575_RS16195 (HF575_16235) letA 3451482..3452138 (+) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HF575_RS16200 (HF575_16240) uvrC 3452135..3453967 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HF575_RS16205 (HF575_16245) pgsA 3454024..3454572 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HF575_RS16225 (HF575_16265) - 3455268..3456008 (-) 741 WP_176607786.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=382817 HF575_RS16195 WP_000611338.1 3451482..3452138(+) (letA) [Escherichia coli strain 17MR471]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=382817 HF575_RS16195 WP_000611338.1 3451482..3452138(+) (letA) [Escherichia coli strain 17MR471]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491