Detailed information NTG0382345

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: HEP85_RS22655
• Genome accession: NZ_CP050975
• Coordinates: 5184617..5185741 (-)
• Length: 374 a.a.
• NCBI ID: WP_168529366.1
• Uniprot ID: A0ABW3XRM5
• Organism: Streptomyces sp. RPA4-2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5179617..5190741

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HEP85_RS22630 (HEP85_22870)	cseB	5180049..5180759 (-)	711	WP_168529356.1	two-component system response regulator CseB	-
HEP85_RS22635 (HEP85_22875)	-	5180789..5181385 (-)	597	WP_168529358.1	hypothetical protein	-
HEP85_RS22640 (HEP85_22880)	-	5181436..5181987 (-)	552	WP_168529360.1	SigE family RNA polymerase sigma factor	-
HEP85_RS22645 (HEP85_22885)	-	5182256..5183176 (-)	921	WP_168529362.1	A/G-specific adenine glycosylase	-
HEP85_RS22650 (HEP85_22890)	-	5183664..5184473 (+)	810	WP_168529364.1	hypothetical protein	-
HEP85_RS22655 (HEP85_22895)	disA	5184617..5185741 (-)	1125	WP_168529366.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
HEP85_RS22660 (HEP85_22900)	radA/sms	5185810..5187219 (-)	1410	WP_168529368.1	DNA repair protein RadA	Machinery gene
HEP85_RS22665 (HEP85_22905)	-	5187493..5189252 (+)	1760	Protein_4464	hypothetical protein	-
HEP85_RS22670 (HEP85_22910)	-	5189256..5190116 (-)	861	WP_168529370.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40178.04 Da
• Isoelectric Point: 5.0058

>NTDB_id=382345 HEP85_RS22655 WP_168529366.1 5184617..5185741(-) (disA) [Streptomyces sp. RPA4-2]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVIDKDLTKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELNALAHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=382345 HEP85_RS22655 WP_168529366.1 5184617..5185741(-) (disA) [Streptomyces sp. RPA4-2]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCATT
GAGCGCCGTGGCACCCGGCACGGCCCTGCGCGACGGGCTCGAACGAATTCTCCGCGGCAACACCGGCGGACTCATCGTGC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGCACCGGCGGCTTCGTACTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGATCGACAAGGACCTCACCAAGATCCTCCGGGCGGGCGTGCAACTGGTGCC
GGACCCGACGATCCCCACCGAGGAGACGGGTACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTCATCGCCCTCTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCCGCCGCG
ATCCTCTCGCGTGCCAACCAGGCTCTCGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTCTC
CGCACTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGTCGGCGGTGGCCCAGCGTCTGGAGATGGTGCGCCGCATCG
CGACCGAGATCGCCGAGTACGTGGTGGAGTTGGGCACCGACGGACGTCTGCTCGCCCTCCAGCTCGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGTGAGCTGGTGGTCCGCGACTACGTGCCCGAGCCCACCGCGAAGCGCTCCCGCACGGTCGACGA
GGCCCTCTTCGAGCTGAACGCCCTCGCCCATGCCGAGCTGCTCGAACTGCCCACGGTGGCAAGGGCGTTGGGTTACACCG
GCTCCCCCGAGGCACTCGACTCCGCGGTCTCGCCGCGCGGCTTCCGGCTCCTCGCGAAGGTCCCGCGTCTGCCCGGCGCG
ATCATCGACCGTCTCGTCGAGCACTTCGGCGGTCTGCAGAAGCTTCTCGCGGCCAGCGTCGACGATCTCCAGGCGGTCGA
CGGGGTGGGCGAGGCGCGGGCGCGCAGCGTACGCGAGGGGCTTTCGCGGCTGGCGGAGTCGTCGATCCTGGAACGGTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433