Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HCU71_RS10760 Genome accession   NZ_CP050691
Coordinates   2239931..2241193 (-) Length   420 a.a.
NCBI ID   WP_000472302.1    Uniprot ID   P63789
Organism   Staphylococcus aureus strain PMB196-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2234931..2246193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCU71_RS10735 (HCU71_10735) - 2235129..2235797 (-) 669 WP_000805951.1 uroporphyrinogen-III synthase -
  HCU71_RS10740 (HCU71_10740) hemC 2235819..2236745 (-) 927 WP_001230232.1 hydroxymethylbilane synthase -
  HCU71_RS10745 (HCU71_10745) - 2236787..2237602 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  HCU71_RS10750 (HCU71_10750) hemA 2237624..2238970 (-) 1347 WP_167780462.1 glutamyl-tRNA reductase -
  HCU71_RS10755 (HCU71_10755) yihA 2239187..2239777 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HCU71_RS10760 (HCU71_10760) clpX 2239931..2241193 (-) 1263 WP_000472302.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HCU71_RS10765 (HCU71_10765) tig 2241344..2242645 (-) 1302 WP_000127573.1 trigger factor -
  HCU71_RS10770 (HCU71_10770) - 2242693..2242803 (-) 111 WP_001790560.1 hypothetical protein -
  HCU71_RS10775 (HCU71_10775) - 2242808..2243737 (-) 930 WP_001280022.1 hypothetical protein -
  HCU71_RS10780 (HCU71_10780) - 2243756..2244364 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  HCU71_RS10785 (HCU71_10785) rplT 2244506..2244862 (-) 357 WP_167780463.1 50S ribosomal protein L20 -
  HCU71_RS10790 (HCU71_10790) rpmI 2244909..2245109 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  HCU71_RS10795 (HCU71_10795) infC 2245138..2245665 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46297.48 Da        Isoelectric Point: 4.2645

>NTDB_id=381671 HCU71_RS10760 WP_000472302.1 2239931..2241193(-) (clpX) [Staphylococcus aureus strain PMB196-1]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=381671 HCU71_RS10760 WP_000472302.1 2239931..2241193(-) (clpX) [Staphylococcus aureus strain PMB196-1]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63789

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531