Detailed information NTG0381026

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: HB370_RS22920
• Genome accession: NZ_CP050504
• Coordinates: 5025550..5026674 (-)
• Length: 374 a.a.
• NCBI ID: WP_030781598.1
• Uniprot ID: A0ABQ3RJX6
• Organism: Streptomyces sp. DSM 40868
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5020550..5031674

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB370_RS22895 (HB370_22895)	cseB	5021336..5022034 (-)	699	WP_030781612.1	two-component system response regulator CseB	-
HB370_RS22900 (HB370_22900)	-	5022073..5022672 (-)	600	WP_037701471.1	hypothetical protein	-
HB370_RS22905 (HB370_22905)	-	5022714..5023253 (-)	540	WP_030781607.1	SigE family RNA polymerase sigma factor	-
HB370_RS22910 (HB370_22910)	-	5023528..5024403 (-)	876	WP_030781604.1	A/G-specific adenine glycosylase	-
HB370_RS22915 (HB370_22915)	-	5024583..5025419 (+)	837	WP_208974431.1	hypothetical protein	-
HB370_RS22920 (HB370_22920)	disA	5025550..5026674 (-)	1125	WP_030781598.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
HB370_RS22925 (HB370_22925)	radA	5026756..5028165 (-)	1410	WP_030781596.1	DNA repair protein RadA	Machinery gene
HB370_RS22930 (HB370_22930)	-	5028353..5030236 (+)	1884	WP_037701486.1	hypothetical protein	-
HB370_RS22935 (HB370_22935)	-	5030285..5031142 (-)	858	WP_030781592.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 39980.71 Da
• Isoelectric Point: 4.9235

>NTDB_id=381026 HB370_RS22920 WP_030781598.1 5025550..5026674(-) (disA) [Streptomyces sp. DSM 40868]
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTPLRDGLERVLRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPDRELVVRDYVPEPTAKRSRTVEEALAELDALTHAELLELGTVARALGYTASPESLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=381026 HB370_RS22920 WP_030781598.1 5025550..5026674(-) (disA) [Streptomyces sp. DSM 40868]
GTGGCAGCCAACGACCGGGCAGCGGCTCCCGGCAAGTCCGGTGGGAGTGCCGGTTCCGACGGTCTGATGCGCGCCTCGCT
GAGCGCCGTGGCGCCGGGCACGCCCCTGCGCGACGGCCTGGAACGGGTTCTGCGCGGCAACACCGGCGGTCTCATCGTCC
TCGGCTCGGACAAGACGGTCGAGGCGATGTGCACGGGCGGGTTCGTGCTGGACGTCGAGTTCACGGCCACCCGGCTGCGG
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTGTCGTCGGACCTGTCGAAGATCCTGCGCGCGGGCGTCCAGCTGGTGCC
GGACCCGACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACGGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCGG
TGGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCCCTGTACGTGGACGGTCAGCGGCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCGCTGGCGACGCTGGAGCGGTACAAGCTGCGGCTGGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCGGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGCTGGGCACCGACGGCCGGCTTCTCGCGCTCCAGCTGGAGGAGCTGATCGCG
GGGGTCGAGCCGGACCGCGAGCTGGTCGTCCGCGACTATGTGCCCGAGCCGACGGCGAAGCGGTCCCGCACGGTCGAGGA
GGCGCTGGCCGAGCTGGACGCGCTGACCCACGCGGAACTGCTGGAACTGGGCACGGTGGCGCGTGCGCTGGGCTACACCG
CGTCGCCCGAGTCGCTGGACTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGGGGCCTGCAGAAGCTGCTGGCCGCGAGCGTGGACGACCTGCAGACCGTGGA
CGGCGTGGGCGAGGCGCGGGCGCGCAGCGTACGGGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	47.11	92.513	0.436