Detailed information NTG0379162

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: HB729_RS09135
• Genome accession: NZ_CP050333
• Coordinates: 1928322..1929602 (+)
• Length: 426 a.a.
• NCBI ID: WP_003087924.1
• Uniprot ID: Q02KU5
• Organism: Pseudomonas aeruginosa strain DVT412
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1923322..1934602

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB729_RS09115 (HB729_09125)	parS	1923946..1925232 (-)	1287	WP_003087912.1	sensor histidine kinase ParS	-
HB729_RS09120 (HB729_09130)	parR	1925233..1925940 (-)	708	WP_003098126.1	response regulator transcription factor ParR	-
HB729_RS09125 (HB729_09135)	tig	1926172..1927482 (+)	1311	WP_003087920.1	trigger factor	-
HB729_RS09130 (HB729_09140)	clpP	1927576..1928217 (+)	642	WP_003098129.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
HB729_RS09135 (HB729_09145)	clpX	1928322..1929602 (+)	1281	WP_003087924.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
HB729_RS09140 (HB729_09150)	lon	1929734..1932130 (+)	2397	WP_003124759.1	endopeptidase La	-
HB729_RS09145 (HB729_09155)	hupB	1932266..1932538 (+)	273	WP_003087931.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46991.78 Da
• Isoelectric Point: 4.8347

>NTDB_id=379162 HB729_RS09135 WP_003087924.1 1928322..1929602(+) (clpX) [Pseudomonas aeruginosa strain DVT412]
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSGHKLPAPKEIRTILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKDDIELGKSNILMIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFAGLERVIQNRSARGGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVKFGLIPEFVGRLPVIATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDE
SVIDGSSQPLMIYENSEKPAKAAPEA

Nucleotide

• Length: 1281 bp

>NTDB_id=379162 HB729_RS09135 WP_003087924.1 1928322..1929602(+) (clpX) [Pseudomonas aeruginosa strain DVT412]
ATGACTGATACCCGCAACGGCGAGGACAACGGCAAGCTGCTGTATTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTGCG
CAAGTTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGTGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCGCAGGCGGAAAGTAGTGGGCACAAACTTCCGGCGCCGAAAGAGATCCGCACCATCCTCGATCAGTACGTGATC
GGGCAGGAGCGGGCCAAGAAGGTTCTGGCGGTAGCGGTATACAACCACTACAAGCGCCTCAACCAGCGTGACAAGAAGGA
CGATATCGAGCTCGGCAAGAGCAACATTCTGATGATCGGCCCAACCGGCTCGGGCAAGACCCTGCTGGCCGAGACCCTCG
CACGTCTGCTGAACGTGCCGTTCACCATCGCCGATGCGACCACGCTGACGGAAGCGGGCTACGTGGGCGAGGATGTCGAG
AACATCATCCAGAAGCTCTTGCAGAAGTGCGATTACGATGTGGAGAAGGCCCAGATGGGCATCGTCTACATCGACGAGAT
CGACAAGATCTCCCGGAAATCGGACAACCCCTCCATCACTCGCGACGTTTCCGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGCTCATCGAGGGCACCGTTGCCTCGGTACCGCCGCAGGGCGGTCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGAT
ACGCGCAACATCCTGTTCATCTGCGGCGGCGCTTTCGCCGGTCTGGAGCGGGTCATCCAGAACCGTTCCGCGCGCGGCGG
CATCGGTTTCAATGCCGAAGTGCGCAGTCAGGAGATGGGCAAGAAGGTCGGCGAGGCGTTCAAGGAAGTCGAACCGGAAG
ATCTCGTCAAGTTCGGTCTTATTCCCGAGTTTGTAGGGCGTTTGCCGGTGATCGCGACTCTTGATGAGCTCGACGAGGCT
GCGCTCATGCAGATCCTGACCGAGCCGAAGAACGCTCTCACCAAGCAGTACGCCAAGCTGTTCGAAATGGAAGGCGTCGA
TCTCGAATTCCGTCCGGACGCACTCAAGGCGGTTGCCCGCAAGGCGCTCGAACGCAAGACCGGTGCACGTGGCTTGCGTT
CAATTCTCGAAGGTATCCTTCTCGATACCATGTACGAGATTCCCTCCCAGCAGGATGTCAGCAAGGTGGTCATCGATGAG
AGTGTCATCGATGGCTCGTCGCAACCCCTGATGATCTACGAGAACAGCGAAAAGCCAGCCAAGGCTGCGCCTGAGGCATG
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (113-311)

3D structure

• AlphaFold DB: Q02KU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	60.934	95.54	0.582
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.198	94.836	0.523