Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HB750_RS03595 Genome accession   NZ_CP050273
Coordinates   706026..707813 (+) Length   595 a.a.
NCBI ID   WP_002265578.1    Uniprot ID   -
Organism   Streptococcus mutans strain P1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 701026..712813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB750_RS03570 (HB750_03570) - 701106..701747 (+) 642 WP_002265582.1 DUF4352 domain-containing protein -
  HB750_RS03575 (HB750_03575) eno 702143..703441 (+) 1299 WP_002263196.1 surface-displayed alpha-enolase -
  HB750_RS03580 (HB750_03580) - 703505..703801 (+) 297 WP_002265581.1 TetR/AcrR family transcriptional regulator -
  HB750_RS03585 (HB750_03585) - 704015..704710 (+) 696 WP_002269348.1 YjjG family noncanonical pyrimidine nucleotidase -
  HB750_RS03590 (HB750_03590) - 704754..705908 (-) 1155 WP_002288016.1 low temperature requirement protein A -
  HB750_RS03595 (HB750_03595) uvrC 706026..707813 (+) 1788 WP_002265578.1 excinuclease ABC subunit UvrC Machinery gene
  HB750_RS03600 (HB750_03600) - 707960..708562 (+) 603 WP_002271686.1 nitroreductase family protein -
  HB750_RS03605 (HB750_03605) pepV 708577..709983 (+) 1407 WP_167311820.1 dipeptidase PepV -
  HB750_RS03610 (HB750_03610) - 710056..710643 (+) 588 WP_002264094.1 uracil-DNA glycosylase family protein -
  HB750_RS03615 (HB750_03615) - 710772..711074 (-) 303 WP_002265575.1 ArsR/SmtB family transcription factor -
  HB750_RS03620 (HB750_03620) - 711165..711515 (+) 351 WP_002265574.1 nuclear transport factor 2 family protein -
  HB750_RS03625 (HB750_03625) - 711533..712336 (+) 804 WP_002265573.1 amidohydrolase family protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68894.26 Da        Isoelectric Point: 9.3062

>NTDB_id=377984 HB750_RS03595 WP_002265578.1 706026..707813(+) (uvrC) [Streptococcus mutans strain P1]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTICQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRDIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLDGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAENIQESLREEREKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=377984 HB750_RS03595 WP_002265578.1 706026..707813(+) (uvrC) [Streptococcus mutans strain P1]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTGCGTAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTGGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCATTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGCATTGGTCTGTTGCGAACCAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGCTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAGTCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAGATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTGTTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATGTAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGCTGGACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCAGAGAACATTCAAGAGAG
CTTGCGAGAGGAAAGAGAAAAAGGTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

77.066

99.664

0.768
  uvrC Streptococcus pneumoniae R6

76.728

99.664

0.765
  uvrC Streptococcus pneumoniae D39

76.728

99.664

0.765

Multiple sequence alignment