Detailed information NTG0377936

Bioinformatically predicted

Overview

• Name: scnR
• Type: Regulator
• Locus tag: HB751_RS09930
• Genome accession: NZ_CP050272
• Coordinates: 2027306..2028004 (+)
• Length: 232 a.a.
• NCBI ID: WP_002263491.1
• Uniprot ID: Q8DSH0
• Organism: Streptococcus mutans strain P6
• Function: regulate comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 2022306..2033004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB751_RS09905 (HB751_09905)	gatC	2022496..2022798 (+)	303	WP_002263475.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
HB751_RS09910 (HB751_09910)	gatA	2022798..2024264 (+)	1467	WP_002274738.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	-
HB751_RS09915 (HB751_09915)	gatB	2024264..2025703 (+)	1440	WP_065868572.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	-
HB751_RS10540	-	2025842..2026255 (+)	414	Protein_1927	transposase	-
HB751_RS10425 (HB751_09925)	-	2026248..2027201 (+)	954	Protein_1928	reverse transcriptase domain-containing protein	-
HB751_RS09930 (HB751_09930)	scnR	2027306..2028004 (+)	699	WP_002263491.1	response regulator transcription factor	Regulator
HB751_RS09935 (HB751_09935)	-	2028022..2029400 (+)	1379	Protein_1930	sensor histidine kinase	-
HB751_RS10545	-	2029757..2029878 (-)	122	Protein_1931	helix-turn-helix domain-containing protein	-
HB751_RS09940 (HB751_09940)	-	2029986..2031235 (-)	1250	Protein_1932	ISL3-like element ISSmu2 family transposase	-
HB751_RS09945 (HB751_09945)	-	2031510..2031668 (+)	159	WP_002268660.1	lacticin 481 family lantibiotic	-
HB751_RS09950 (HB751_09950)	-	2031695..2031847 (+)	153	WP_002269377.1	lacticin 481 family lantibiotic	-
HB751_RS09955 (HB751_09955)	-	2031887..2032042 (+)	156	WP_002296231.1	lacticin 481 family lantibiotic	-
HB751_RS09960 (HB751_09960)	-	2032236..2032397 (+)	162	WP_002268661.1	type A2 lanthipeptide	-

Sequence

Protein

• Length: 232 a.a.
• Molecular weight: 26106.25 Da
• Isoelectric Point: 6.3461

>NTDB_id=377936 HB751_RS09930 WP_002263491.1 2027306..2028004(+) (scnR) [Streptococcus mutans strain P6]
MSFESQLLKKHILIVDDDTSLNQSIKEVLMSRGFNNISSAYSIDEGIDIFSVSKIDLIILDVMLPDGEGYLLAKYIRKSS
DVPILFLTAKNSPDDEIKGLDSGGDDFVTKPFLPKTLSYRIIALLRRSYKGESELIELTFCTIDLNNASVLKGNEHLSLT
PTEIQILRKLYVNKNHIVSTEAICDAVWGLENFGYEKSLMVHIRNIREKIEKNSSKPVHLITVKGLGYKLVI

Nucleotide

• Length: 699 bp

>NTDB_id=377936 HB751_RS09930 WP_002263491.1 2027306..2028004(+) (scnR) [Streptococcus mutans strain P6]
GTGTCTTTTGAATCACAATTATTGAAAAAGCATATCCTAATCGTAGATGATGATACATCATTGAACCAGTCCATCAAAGA
GGTTTTGATGAGTCGAGGGTTTAACAATATCAGTTCTGCCTATAGTATAGATGAAGGGATTGATATTTTTTCGGTATCAA
AGATTGATTTGATCATACTGGATGTCATGTTGCCCGATGGGGAAGGTTATTTATTGGCCAAATACATTCGAAAATCGTCA
GATGTCCCTATTTTATTTTTAACCGCAAAAAATAGTCCCGATGATGAAATCAAAGGACTTGATTCAGGAGGAGATGATTT
TGTCACCAAACCATTTCTTCCCAAGACCCTGTCTTATAGGATTATAGCCTTACTGAGGCGATCCTACAAAGGTGAATCTG
AACTTATCGAACTTACTTTCTGCACCATTGATTTAAATAATGCCAGTGTTTTAAAAGGCAATGAACATCTATCACTGACC
CCAACAGAAATTCAGATTCTTCGCAAACTTTATGTCAATAAAAACCATATCGTCTCCACAGAAGCGATTTGCGATGCGGT
GTGGGGACTTGAAAACTTTGGATACGAAAAATCATTAATGGTACATATCCGCAATATCAGAGAAAAAATCGAGAAAAACT
CCTCAAAGCCAGTGCATCTCATTACAGTCAAGGGTCTCGGGTATAAGCTGGTCATTTAG

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (12-120)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

3D structure

• AlphaFold DB: Q8DSH0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
scnR	Streptococcus mutans UA159	42.411	96.552	0.409
vicR	Streptococcus mutans UA159	37.826	99.138	0.375
micA	Streptococcus pneumoniae Cp1015	36.842	98.276	0.362