Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FRG19_RS04645 Genome accession   NZ_CP042341
Coordinates   995011..995640 (+) Length   209 a.a.
NCBI ID   WP_002469716.1    Uniprot ID   -
Organism   Staphylococcus capitis strain BN2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 990011..1000640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FRG19_RS04615 (FRG19_04605) isaB 990193..990735 (+) 543 WP_002435927.1 immunodominant staphylococcal antigen IsaB family protein -
  FRG19_RS04620 (FRG19_04610) - 990813..991802 (-) 990 WP_002435886.1 FUSC family protein -
  FRG19_RS04625 (FRG19_04615) map 991976..992731 (+) 756 WP_002435911.1 type I methionyl aminopeptidase -
  FRG19_RS04630 (FRG19_04620) - 992876..993262 (+) 387 WP_194251441.1 hypothetical protein -
  FRG19_RS04635 (FRG19_04625) liaF 993277..993978 (+) 702 WP_002435891.1 cell wall-active antibiotics response protein LiaF -
  FRG19_RS04640 (FRG19_04630) vraS 993975..995021 (+) 1047 WP_002435929.1 sensor histidine kinase Regulator
  FRG19_RS04645 (FRG19_04635) vraR 995011..995640 (+) 630 WP_002469716.1 two-component system response regulator VraR Regulator
  FRG19_RS04650 (FRG19_04640) - 995705..996958 (-) 1254 WP_002435884.1 YihY/virulence factor BrkB family protein -
  FRG19_RS04655 (FRG19_04645) - 997295..997579 (-) 285 WP_002435890.1 hypothetical protein -
  FRG19_RS04660 (FRG19_04650) - 997586..998050 (-) 465 WP_002435947.1 low molecular weight protein-tyrosine-phosphatase -
  FRG19_RS04665 (FRG19_04655) - 998191..998397 (+) 207 WP_049427714.1 DUF1128 domain-containing protein -
  FRG19_RS04670 (FRG19_04660) - 998411..999652 (+) 1242 WP_049427715.1 aminopeptidase -
  FRG19_RS04675 (FRG19_04665) - 999755..1000285 (+) 531 WP_002453596.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23645.28 Da        Isoelectric Point: 4.8997

>NTDB_id=377153 FRG19_RS04645 WP_002469716.1 995011..995640(+) (vraR) [Staphylococcus capitis strain BN2]
MAIKVLFVDDHEMVRIGISSYLSTQQDIEVVGEGASGKEAIEKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPHIRVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYQGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=377153 FRG19_RS04645 WP_002469716.1 995011..995640(+) (vraR) [Staphylococcus capitis strain BN2]
ATGGCGATTAAAGTATTGTTTGTTGATGACCATGAAATGGTTAGAATTGGTATTTCAAGCTATCTATCTACACAACAGGA
TATTGAAGTAGTTGGAGAAGGTGCTTCTGGTAAAGAAGCTATCGAAAAAGCCCATGAGTTGAAACCAGATTTAATTTTAA
TGGATTTACTTATGGATGATATGGATGGTGTAGAAGCTACTACTGAAATTAAAAAGGATTTACCTCACATAAGAGTAGTA
ATGTTAACAAGCTTTATCGAGGATAAAGAAGTTTATCGAGCATTAGATGCTGGGGTAGATAGTTATATCTTAAAAACGAC
TAGTGCGAGTGACATTGCTGACGCGGTACGTAAAACATATCAAGGGGAATCTGTTTTTGAACCAGAAGTACTTGTAAAAA
TGAGAAACCGCATGAAAAAACGTGCTGAGTTATATGAAATGCTTACAGAGCGTGAAATGGAAATTTTATTATTAATTGCC
AAAGGTTACTCTAACCAAGAAATTGCTAGCGCCTCTCATATCACTATTAAAACTGTTAAAACACACGTAAGTAATATATT
GAGTAAGTTAGAAGTTCAAGATAGAACTCAAGCTGTTATTTATGCTTTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364

Multiple sequence alignment