Detailed information NTG0037664

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: HPB8_RS07505
• Genome accession: NC_014256
• Coordinates: 1554587..1555642 (-)
• Length: 351 a.a.
• NCBI ID: WP_000786677.1
• Uniprot ID: D7FG37
• Organism: Helicobacter pylori B8
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1549587..1560642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPB8_RS07480 (HPB8_1582)	-	1550124..1551536 (-)	1413	WP_001861341.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
HPB8_RS07485 (HPB8_1583)	comB10	1551606..1552742 (-)	1137	WP_001045869.1	DNA type IV secretion system protein ComB10	Machinery gene
HPB8_RS07490 (HPB8_1584)	comB9	1552735..1553718 (-)	984	WP_001861340.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPB8_RS07495 (HPB8_1585)	comB8	1553718..1554461 (-)	744	WP_000660520.1	type IV secretion system protein	Machinery gene
HPB8_RS07500 (HPB8_1586)	comB7	1554458..1554571 (-)	114	WP_001217873.1	hypothetical protein	Machinery gene
HPB8_RS07505 (HPB8_1587)	comB6	1554587..1555642 (-)	1056	WP_000786677.1	P-type conjugative transfer protein TrbL	Machinery gene
HPB8_RS07510 (HPB8_1588)	-	1555650..1556645 (-)	996	WP_000468428.1	PDZ domain-containing protein	-
HPB8_RS07515 (HPB8_1589)	-	1556645..1556947 (-)	303	WP_000347926.1	YbaB/EbfC family nucleoid-associated protein	-
HPB8_RS07520 (HPB8_1590)	panD	1556950..1557303 (-)	354	WP_000142236.1	aspartate 1-decarboxylase	-
HPB8_RS07525 (HPB8_1591)	-	1557293..1559518 (-)	2226	WP_001051506.1	AAA family ATPase	-
HPB8_RS07530 (HPB8_1592)	-	1559518..1559793 (-)	276	WP_000784899.1	ATP-dependent Clp protease adaptor ClpS	-
HPB8_RS07535 (HPB8_1593)	-	1559808..1560221 (-)	414	WP_001023005.1	universal stress protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39908.89 Da
• Isoelectric Point: 8.5786

>NTDB_id=37664 HPB8_RS07505 WP_000786677.1 1554587..1555642(-) (comB6) [Helicobacter pylori B8]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSASALTEALWFVGFFALFNY
ALKNPMHFYEFFQNAIFIAPNMIAQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQGLFLSVL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVVICLKKCFALGFYKPFLLLVGFLNVSVTKALIDAHMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSANLSQNALNSLQYITTPPAPSSVSSSMNESVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=37664 HPB8_RS07505 WP_000786677.1 1554587..1555642(-) (comB6) [Helicobacter pylori B8]
ATGAAAAATGACGCTTATGAGATTATTCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTCGCTGAATT
TTTTCTCTACACTTTGCATGCGCAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTTTTTGCTTACAGGAGCT
TGAAGGAACAGAATTTCTTCAGCGCCAGCGCACTAACAGAAGCGTTATGGTTTGTGGGGTTTTTTGCGCTGTTTAACTAC
GCTTTAAAAAATCCCATGCATTTTTATGAATTTTTCCAAAACGCTATTTTTATTGCGCCTAACATGATCGCGCAGAGCCT
CTCTCAAAGCTTGAGTAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATCTTTAATCATGGTTTTTATGCCCTTAGTT
TTATCAGCGATTTGAGCCATAATGAAATGTCTGTGTGGCTTTTTTTAAGCATTTTGCAAGGGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTAGGGGTGCTGTTTTTAGCGTTTGGGTTTTT
CAAAACCTGGAGGAGCGTTGTGGTTATATGCCTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTGG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCTTTAATAGACGCTCATATGCAAGAAAAACAAGATTTAAGCCTTTTATTG
GTGGTAGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCCACCAATTTGAGCGCTAACCTCAGCCAAAACGCCCTTAATTCCTTACAATATATCA
CGACCCCACCCGCTCCCTCTAGCGTTTCTTCTTCTATGAATGAAAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACT
TTTAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: D7FG37

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	98.575	100	0.986