Detailed information NTG0037655

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HPB8_RS05815
• Genome accession: NC_014256
• Coordinates: 1203576..1204376 (-)
• Length: 266 a.a.
• NCBI ID: WP_000835251.1
• Uniprot ID: D7FF31
• Organism: Helicobacter pylori B8
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1198576..1209376

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPB8_RS05785 (HPB8_1224)	recJ	1198926..1200476 (+)	1551	WP_000810776.1	single-stranded-DNA-specific exonuclease RecJ	-
HPB8_RS05790 (HPB8_1225)	-	1200476..1201372 (+)	897	WP_001117136.1	RluA family pseudouridine synthase	-
HPB8_RS05795 (HPB8_1226)	-	1201505..1202065 (-)	561	WP_000037134.1	hypothetical protein	-
HPB8_RS05800 (HPB8_1227)	-	1202049..1202387 (-)	339	WP_000699916.1	hypothetical protein	-
HPB8_RS05805 (HPB8_1229)	-	1202575..1203117 (-)	543	WP_000892212.1	tetratricopeptide repeat protein	-
HPB8_RS05810 (HPB8_1230)	dprB	1203175..1203579 (-)	405	WP_000599159.1	Holliday junction resolvase RuvX	Machinery gene
HPB8_RS05815 (HPB8_1231)	dprA	1203576..1204376 (-)	801	WP_000835251.1	DNA-processing protein DprA	Machinery gene
HPB8_RS05820 (HPB8_1232)	minE	1204383..1204616 (-)	234	WP_000051414.1	cell division topological specificity factor MinE	-
HPB8_RS05825 (HPB8_1233)	minD	1204613..1205419 (-)	807	WP_001019050.1	septum site-determining protein MinD	-
HPB8_RS05830 (HPB8_1234)	ilvC	1205443..1206435 (-)	993	WP_001207748.1	ketol-acid reductoisomerase	-
HPB8_RS05840 (HPB8_1235)	-	1206684..1207466 (+)	783	WP_001168242.1	NAD+ synthase	-
HPB8_RS05845 (HPB8_1236)	-	1207463..1208401 (+)	939	WP_000833945.1	tetraacyldisaccharide 4'-kinase	-
HPB8_RS05850	pseH	1208334..1208876 (-)	543	WP_000742654.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29879.74 Da
• Isoelectric Point: 6.9617

>NTDB_id=37655 HPB8_RS05815 WP_000835251.1 1203576..1204376(-) (dprA) [Helicobacter pylori B8]
MKSHFQYSVLENIPKAFDILKDPPKQLYCVGDIKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPTTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMEDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=37655 HPB8_RS05815 WP_000835251.1 1203576..1204376(-) (dprA) [Helicobacter pylori B8]
ATGAAAAGCCATTTCCAATACAGCGTACTAGAAAATATCCCTAAAGCCTTTGACATACTCAAAGACCCTCCTAAACAGCT
CTATTGTGTGGGCGATATAAAGCTTTTAGAAGCGCCTTTAAAAGTGGCGATCATAGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAACAACGATCATGCTTTCGCCTTGCAGTTTGGATTTTATCTATCCTACGAA
CAATCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTTATGCCCATTAAAG
GCTCTTTTTTAGCCAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTGATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAACCCTTGTTTGTTTTACCCCAACGCCTGAATGAAAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGGAAGATGAATTTTTAGAATATTGTGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (13-197)

3D structure

• AlphaFold DB: D7FF31

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	97.368	100	0.974
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.673	84.962	0.414