Detailed information
Bioinformatically predicted
Overview
| Name | sepM | Type | Regulator |
| Locus tag | HMPREF0837_RS10815 | Genome accession | NC_014251 |
| Coordinates | 2048472..2049509 (-) | Length | 345 a.a. |
| NCBI ID | WP_000727280.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae TCH8431/19A | ||
| Function | processing of CSP (predicted from homology) Competence regulation |
||
Genomic Context
Location: 2043472..2054509
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HMPREF0837_RS10790 (HMPREF0837_12231) | - | 2044211..2045542 (-) | 1332 | WP_000390039.1 | hemolysin family protein | - |
| HMPREF0837_RS10795 (HMPREF0837_12232) | endA | 2045833..2046657 (-) | 825 | WP_001036785.1 | DNA-entry nuclease EndA | Machinery gene |
| HMPREF0837_RS10800 (HMPREF0837_12233) | - | 2046696..2046884 (-) | 189 | WP_001036519.1 | DNA-directed RNA polymerase subunit beta | - |
| HMPREF0837_RS10805 (HMPREF0837_12234) | murA | 2046877..2048160 (-) | 1284 | WP_000358028.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| HMPREF0837_RS10810 (HMPREF0837_12235) | - | 2048184..2048414 (-) | 231 | WP_000615437.1 | DUF1146 family protein | - |
| HMPREF0837_RS10815 (HMPREF0837_12236) | sepM | 2048472..2049509 (-) | 1038 | WP_000727280.1 | SepM family pheromone-processing serine protease | Regulator |
| HMPREF0837_RS10820 (HMPREF0837_12237) | coaD | 2049493..2049981 (-) | 489 | WP_001280766.1 | pantetheine-phosphate adenylyltransferase | - |
| HMPREF0837_RS10825 (HMPREF0837_12238) | rsmD | 2049971..2050510 (-) | 540 | WP_000706960.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD | - |
| HMPREF0837_RS10830 (HMPREF0837_12239) | asnA | 2050575..2051567 (-) | 993 | WP_000747993.1 | aspartate--ammonia ligase | - |
| HMPREF0837_RS10840 (HMPREF0837_12241) | - | 2051679..2052362 (-) | 684 | WP_001016913.1 | Bax inhibitor-1/YccA family protein | - |
| HMPREF0837_RS10845 (HMPREF0837_12242) | - | 2052418..2053158 (-) | 741 | WP_000152701.1 | RNA methyltransferase | - |
| HMPREF0837_RS10850 (HMPREF0837_12243) | - | 2053192..2053470 (+) | 279 | WP_001174613.1 | acylphosphatase | - |
| HMPREF0837_RS10855 (HMPREF0837_12244) | yidC | 2053548..2054474 (+) | 927 | WP_000835948.1 | membrane protein insertase YidC | - |
Sequence
Protein
Download Length: 345 a.a. Molecular weight: 37567.60 Da Isoelectric Point: 5.0724
>NTDB_id=37640 HMPREF0837_RS10815 WP_000727280.1 2048472..2049509(-) (sepM) [Streptococcus pneumoniae TCH8431/19A]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP
Nucleotide
Download Length: 1038 bp
>NTDB_id=37640 HMPREF0837_RS10815 WP_000727280.1 2048472..2049509(-) (sepM) [Streptococcus pneumoniae TCH8431/19A]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sepM | Streptococcus mutans UA159 |
59.649 |
99.13 |
0.591 |