Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   HMPREF0837_RS10795 Genome accession   NC_014251
Coordinates   2045833..2046657 (-) Length   274 a.a.
NCBI ID   WP_001036785.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2040833..2051657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS10790 (HMPREF0837_12231) - 2044211..2045542 (-) 1332 WP_000390039.1 hemolysin family protein -
  HMPREF0837_RS10795 (HMPREF0837_12232) endA 2045833..2046657 (-) 825 WP_001036785.1 DNA-entry nuclease EndA Machinery gene
  HMPREF0837_RS10800 (HMPREF0837_12233) - 2046696..2046884 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  HMPREF0837_RS10805 (HMPREF0837_12234) murA 2046877..2048160 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  HMPREF0837_RS10810 (HMPREF0837_12235) - 2048184..2048414 (-) 231 WP_000615437.1 DUF1146 family protein -
  HMPREF0837_RS10815 (HMPREF0837_12236) sepM 2048472..2049509 (-) 1038 WP_000727280.1 SepM family pheromone-processing serine protease Regulator
  HMPREF0837_RS10820 (HMPREF0837_12237) coaD 2049493..2049981 (-) 489 WP_001280766.1 pantetheine-phosphate adenylyltransferase -
  HMPREF0837_RS10825 (HMPREF0837_12238) rsmD 2049971..2050510 (-) 540 WP_000706960.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  HMPREF0837_RS10830 (HMPREF0837_12239) asnA 2050575..2051567 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29917.56 Da        Isoelectric Point: 10.0650

>NTDB_id=37639 HMPREF0837_RS10795 WP_001036785.1 2045833..2046657(-) (endA) [Streptococcus pneumoniae TCH8431/19A]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=37639 HMPREF0837_RS10795 WP_001036785.1 2045833..2046657(-) (endA) [Streptococcus pneumoniae TCH8431/19A]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAATGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989

Multiple sequence alignment