Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   G9P51_RS09275 Genome accession   NZ_CP050044
Coordinates   1960536..1961192 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 74-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1955536..1966192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G9P51_RS09235 (G9P51_09265) dcyD 1955639..1956625 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  G9P51_RS09240 (G9P51_09270) tcyL 1956640..1957308 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  G9P51_RS09245 (G9P51_09275) tcyN 1957305..1958057 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  G9P51_RS09250 (G9P51_09280) sdiA 1958287..1958640 (+) 354 Protein_1826 transcriptional regulator SdiA -
  G9P51_RS09260 (G9P51_09290) sdiA 1959406..1959786 (+) 381 Protein_1828 transcriptional regulator SdiA -
  G9P51_RS09265 (G9P51_09295) yecF 1959853..1960077 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  G9P51_RS09270 (G9P51_09300) yecU 1960064..1960240 (-) 177 WP_000590347.1 protein YecU -
  G9P51_RS23955 - 1960323..1960394 (-) 72 Protein_1831 transcriptional regulator -
  G9P51_RS09275 (G9P51_09305) letA 1960536..1961192 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  G9P51_RS09280 (G9P51_09310) uvrC 1961189..1963021 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  G9P51_RS09285 (G9P51_09315) pgsA 1963078..1963626 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  G9P51_RS09305 (G9P51_09335) - 1964322..1965062 (-) 741 WP_000440336.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=376328 G9P51_RS09275 WP_000611335.1 1960536..1961192(+) (letA) [Escherichia coli strain 74-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=376328 G9P51_RS09275 WP_000611335.1 1960536..1961192(+) (letA) [Escherichia coli strain 74-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment