Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HMPREF0837_RS03285 Genome accession   NC_014251
Coordinates   614051..614740 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 609051..619740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS03260 (HMPREF0837_10669) gpsB 609148..609489 (+) 342 WP_000200644.1 cell division regulator GpsB -
  HMPREF0837_RS03270 (HMPREF0837_10670) - 609975..611132 (+) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  HMPREF0837_RS03275 (HMPREF0837_10671) mapZ 611145..612539 (+) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  HMPREF0837_RS03280 (HMPREF0837_10672) gndA 612615..614039 (+) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  HMPREF0837_RS03285 (HMPREF0837_10673) covR 614051..614740 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  HMPREF0837_RS03290 (HMPREF0837_10674) cbpC 614838..615800 (+) 963 WP_000698035.1 choline-binding protein CbpC -
  HMPREF0837_RS03295 (HMPREF0837_10675) cbpJ 615819..616817 (+) 999 WP_000771129.1 choline-binding protein CbpJ -
  HMPREF0837_RS03300 (HMPREF0837_10676) - 616935..618167 (-) 1233 WP_000765684.1 MFS transporter -
  HMPREF0837_RS12300 (HMPREF0837_10677) - 618326..618796 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  HMPREF0837_RS12305 - 618696..619054 (-) 359 Protein_629 lantibiotic-modifying protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=37599 HMPREF0837_RS03285 WP_000518011.1 614051..614740(+) (covR) [Streptococcus pneumoniae TCH8431/19A]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=37599 HMPREF0837_RS03285 WP_000518011.1 614051..614740(+) (covR) [Streptococcus pneumoniae TCH8431/19A]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment