Detailed information NTG0375643

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FP477_RS04380
• Genome accession: NZ_CP042046
• Coordinates: 808267..809154 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain B2-7A
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 803267..814154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FP477_RS04345 (FP477_04345)	-	803295..803378 (+)	84	WP_031797553.1	hypothetical protein	-
FP477_RS04350 (FP477_04350)	-	803486..803983 (-)	498	WP_001065268.1	glutathione peroxidase	-
FP477_RS04355 (FP477_04355)	-	803993..804253 (-)	261	WP_001789307.1	hypothetical protein	-
FP477_RS04365 (FP477_04365)	-	804635..804748 (-)	114	WP_011447078.1	hypothetical protein	-
FP477_RS04370 (FP477_04370)	-	805407..807407 (-)	2001	WP_000776733.1	ABC transporter permease	-
FP477_RS04375 (FP477_04375)	-	807404..808159 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FP477_RS04380 (FP477_04380)	braS	808267..809154 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FP477_RS04385 (FP477_04385)	braR	809165..809830 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FP477_RS04390 (FP477_04390)	-	809856..810056 (-)	201	WP_000604727.1	hypothetical protein	-
FP477_RS04395 (FP477_04395)	-	810254..811678 (+)	1425	WP_000953744.1	alkaline phosphatase	-
FP477_RS14735 (FP477_04400)	-	811738..811839 (-)	102	WP_000731972.1	SE2200 family small protein	-
FP477_RS04405 (FP477_04405)	-	811961..812416 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FP477_RS04410 (FP477_04410)	-	812661..813422 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=375643 FP477_RS04380 WP_000143419.1 808267..809154(-) (braS) [Staphylococcus aureus strain B2-7A]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=375643 FP477_RS04380 WP_000143419.1 808267..809154(-) (braS) [Staphylococcus aureus strain B2-7A]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997