Detailed information NTG0375001

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FPL13_RS03145
• Genome accession: NZ_CP041968
• Coordinates: 635641..636873 (+)
• Length: 410 a.a.
• NCBI ID: WP_049512931.1
• Uniprot ID: A0A7L8W6W9
• Organism: Streptococcus sp. KS 6
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 630641..641873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPL13_RS03115 (FPL13_03160)	-	631427..632269 (+)	843	WP_192208673.1	phosphate ABC transporter ATPase	-
FPL13_RS03120 (FPL13_03165)	-	632308..632574 (+)	267	WP_049512940.1	chorismate mutase	-
FPL13_RS03125 (FPL13_03170)	-	632589..633806 (+)	1218	WP_049512937.1	voltage-gated chloride channel family protein	-
FPL13_RS03130 (FPL13_03175)	-	633892..634731 (+)	840	WP_049512935.1	thymidylate synthase	-
FPL13_RS03135 (FPL13_03180)	-	634917..635429 (+)	513	WP_049512933.1	dihydrofolate reductase	-
FPL13_RS03140 (FPL13_03185)	-	635429..635602 (+)	174	WP_003024903.1	hypothetical protein	-
FPL13_RS03145 (FPL13_03190)	clpX	635641..636873 (+)	1233	WP_049512931.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FPL13_RS03150 (FPL13_03195)	yihA	636885..637472 (+)	588	WP_049512928.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FPL13_RS03155 (FPL13_03200)	-	637594..638301 (+)	708	WP_049512925.1	glucosaminidase domain-containing protein	-
FPL13_RS03160 (FPL13_03205)	-	638474..640219 (+)	1746	WP_049512924.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45661.18 Da
• Isoelectric Point: 4.4242

>NTDB_id=375001 FPL13_RS03145 WP_049512931.1 635641..636873(+) (clpX) [Streptococcus sp. KS 6]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLSILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREDEEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=375001 FPL13_RS03145 WP_049512931.1 635641..636873(+) (clpX) [Streptococcus sp. KS 6]
ATGCCTACAAATCGTACGAATGAAATGATGGTTTATTGCTCTTTTTGTGGTAAAAGCCAAGAAGAAGTCCAAAAAATTAT
CGCAGGAAATAATGCCTTTATTTGTAATGAATGTGTGGAATTAGCACAAGAAATCATCAGAGAGGAACTAGCAGAAGAAG
TGCTAGCAGACTTGTCAGAAGTGCCAAAACCACAAGAACTACTCAGTATTTTGAATCACTATGTGATTGGACAAGACCGT
GCTAAGCGTGCTTTGGCTGTGGCTGTCTATAATCACTATAAACGCATCAATTTTCATGATAATCGTGAAGATGAGGAAGA
TGTCGAATTGCAGAAATCCAATATCCTTATGATTGGTCCAACTGGTTCTGGCAAGACCTTCCTCGCTCAAACCTTGGCAA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCTGAGCGTGGTATCATCTATGTAGATGAGATTGA
CAAAATTGCGAAGAAAAGCGAAAATGTCTCTATTACTCGTGATGTGTCTGGTGAAGGTGTTCAGCAAGCACTCCTCAAGA
TTATTGAAGGAACTGTAGCCAGCGTACCTCCGCAAGGCGGCCGCAAGCATCCTCAACAAGAGATGATTCAAGTAGATACG
AAAAATATTCTCTTTATCGTTGGTGGTGCATTTGACGGTATTGAAGAAATTGTCAAACAACGACTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAACAACAAAGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGCTTGATTCCGGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTAACAGTTGATGATTTGGTGCGA
ATCCTTCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTTCTTTCTTATGATGATGTCAAATTGGAGTTTGA
TGATGACGCTCTTCAGGAAATCGCTAACAAGGCCATTGAACGCAAGACAGGTGCGCGTGGATTACGTTCGATTATCGAGG
AGACTATGATGGATGTCATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGCTGGTACGGATTACTAAGGAAGCAGTTGAC
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

3D structure

• AlphaFold DB: A0A7L8W6W9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.829	100	0.868
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.458	98.049	0.573