Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FPL13_RS01820 Genome accession   NZ_CP041968
Coordinates   372785..373474 (+) Length   229 a.a.
NCBI ID   WP_049513939.1    Uniprot ID   A0A7L8W610
Organism   Streptococcus sp. KS 6     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 367785..378474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS01800 (FPL13_01845) - 368335..369564 (-) 1230 WP_049513933.1 hypothetical protein -
  FPL13_RS01805 (FPL13_01850) - 369754..370611 (-) 858 WP_049513934.1 Rgg/GadR/MutR family transcriptional regulator -
  FPL13_RS01810 (FPL13_01855) - 370724..371260 (+) 537 WP_049513936.1 DUF177 domain-containing protein -
  FPL13_RS01815 (FPL13_01860) gndA 371352..372776 (+) 1425 WP_049513937.1 NADP-dependent phosphogluconate dehydrogenase -
  FPL13_RS01820 (FPL13_01865) covR 372785..373474 (+) 690 WP_049513939.1 DNA-binding response regulator Regulator
  FPL13_RS01825 (FPL13_01870) - 373685..375874 (+) 2190 WP_049513940.1 PTS transporter subunit IIBC -
  FPL13_RS01830 (FPL13_01875) - 375891..376705 (+) 815 Protein_356 endonuclease/exonuclease/phosphatase family protein -
  FPL13_RS09680 (FPL13_01880) - 376752..377228 (-) 477 WP_225620259.1 hypothetical protein -
  FPL13_RS01835 (FPL13_01885) nrdR 377529..378002 (+) 474 WP_049513943.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26384.45 Da        Isoelectric Point: 6.7323

>NTDB_id=374994 FPL13_RS01820 WP_049513939.1 372785..373474(+) (covR) [Streptococcus sp. KS 6]
MAKRILLVEKEKRLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTAFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVADLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=374994 FPL13_RS01820 WP_049513939.1 372785..373474(+) (covR) [Streptococcus sp. KS 6]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAGGTTAGCACAATTTATTGGCTTAGAACTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTAGCGTCTGCGCGAGCGAATCAATATGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGCATTTGCTGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GGCGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGACGTGATTTTATTGATCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
CGAGAATATGATTTATTAGCAACATTGATGGGAAGCCATCAAGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTGTGGAA
ATATGAAGGAGCTGTTGAAACAAATGTTGTTGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGCGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W610

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

100

0.45

Multiple sequence alignment