Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E3226_RS02465 Genome accession   NZ_CP041713
Coordinates   515602..516261 (-) Length   219 a.a.
NCBI ID   WP_028386582.1    Uniprot ID   -
Organism   Legionella geestiana strain HL-0438-4026     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 510602..521261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3226_RS02450 (E3226_002165) - 512385..512924 (-) 540 WP_135842273.1 endopeptidase IV -
  E3226_RS02455 (E3226_002170) - 512924..513643 (-) 720 WP_028386580.1 L,D-transpeptidase -
  E3226_RS02460 (E3226_002175) uvrC 513725..515602 (-) 1878 WP_028386581.1 excinuclease ABC subunit UvrC -
  E3226_RS02465 (E3226_002180) letA 515602..516261 (-) 660 WP_028386582.1 two-component system response regulator LetA Regulator
  E3226_RS02470 (E3226_002185) phhA 516326..517144 (-) 819 WP_028386583.1 phenylalanine 4-monooxygenase -
  E3226_RS02475 (E3226_002190) bioC 517210..518073 (-) 864 WP_028386584.1 malonyl-ACP O-methyltransferase BioC -
  E3226_RS02480 (E3226_002195) - 518112..518804 (+) 693 WP_338011253.1 ComF family protein -
  E3226_RS02485 (E3226_002200) - 518815..519105 (-) 291 WP_028386586.1 hypothetical protein -
  E3226_RS02490 (E3226_002205) hemA 519261..520535 (+) 1275 WP_028386587.1 glutamyl-tRNA reductase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24586.79 Da        Isoelectric Point: 6.8605

>NTDB_id=373346 E3226_RS02465 WP_028386582.1 515602..516261(-) (letA) [Legionella geestiana strain HL-0438-4026]
MIKVLIVDDHALVRMGIRRLLDDLPDVEVVADAESGEQALQMVKQHQPHVVLLDMKMPGIDGWEVTRRLKKSSPQVKVIA
VTAVCAEPLPARVLQLGAMGYLTKECGAGEMAAAIRRVYQGEKYLSAEIARKMAISSLEEPRESPFSQLSEREMQVMLMI
TSGMMVQDIANRLFLSTKTINGYRYRIFEKLCVKNDVELTFLAMQHRVIERPGESDSPS

Nucleotide


Download         Length: 660 bp        

>NTDB_id=373346 E3226_RS02465 WP_028386582.1 515602..516261(-) (letA) [Legionella geestiana strain HL-0438-4026]
TTGATTAAAGTACTCATTGTCGATGACCATGCACTGGTTCGGATGGGTATTCGGCGTTTACTGGATGATTTGCCTGATGT
GGAAGTGGTGGCTGACGCTGAAAGCGGCGAGCAGGCCTTACAGATGGTGAAGCAGCACCAGCCGCATGTGGTATTGCTTG
ATATGAAAATGCCAGGCATTGATGGCTGGGAAGTCACACGGCGTCTTAAAAAATCGAGTCCCCAGGTGAAAGTGATAGCC
GTAACCGCCGTGTGTGCAGAGCCGCTGCCAGCGCGCGTTTTACAACTGGGCGCCATGGGGTATCTGACCAAGGAGTGCGG
TGCAGGTGAGATGGCGGCCGCCATTCGCCGGGTGTATCAGGGCGAAAAATACCTGAGCGCTGAAATTGCTCGAAAAATGG
CAATCAGCAGCCTCGAGGAGCCGCGTGAATCACCGTTCAGTCAGCTCTCCGAGCGTGAAATGCAGGTCATGCTCATGATA
ACGAGCGGCATGATGGTGCAGGATATCGCCAACCGTTTGTTTCTAAGCACAAAAACCATTAATGGATACCGTTATCGCAT
TTTTGAAAAGCTTTGCGTGAAGAACGATGTGGAGCTGACGTTTCTCGCGATGCAGCACCGTGTGATTGAGCGCCCGGGCG
AATCCGACAGTCCCTCCTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

80.841

97.717

0.79
  letA Legionella pneumophila strain ERS1305867

80.841

97.717

0.79

Multiple sequence alignment