Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   G5T40_RS07005 Genome accession   NZ_CP049196
Coordinates   1493201..1493857 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain E118     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1488201..1498857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G5T40_RS06975 dcyD 1489081..1490067 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  G5T40_RS06980 tcyL 1490082..1490750 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  G5T40_RS06985 tcyN 1490747..1491499 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  G5T40_RS06990 sdiA 1491729..1492451 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  G5T40_RS06995 yecF 1492518..1492742 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  G5T40_RS07000 yecU 1492729..1492905 (-) 177 WP_000590347.1 protein YecU -
  G5T40_RS07005 letA 1493201..1493857 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  G5T40_RS07010 uvrC 1493854..1495686 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  G5T40_RS07015 pgsA 1495743..1496291 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  G5T40_RS07035 yecA 1496941..1497606 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=372915 G5T40_RS07005 WP_000611328.1 1493201..1493857(+) (letA) [Escherichia coli strain E118]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=372915 G5T40_RS07005 WP_000611328.1 1493201..1493857(+) (letA) [Escherichia coli strain E118]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482