Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ST64987_RS01000 Genome accession   NZ_CP049053
Coordinates   170012..170761 (+) Length   249 a.a.
NCBI ID   WP_065972842.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST64987     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 165012..175761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS00975 - 165560..165730 (+) 171 WP_023909348.1 hypothetical protein -
  ST64987_RS00980 (ST64987_0147) - 166011..166751 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  ST64987_RS00985 (ST64987_0148) - 166751..168301 (-) 1551 WP_167401407.1 ABC transporter substrate-binding protein/permease -
  ST64987_RS00990 (ST64987_0149) - 168504..169358 (+) 855 WP_014607892.1 undecaprenyl-diphosphate phosphatase -
  ST64987_RS00995 - 169531..169746 (-) 216 WP_011226805.1 DUF3021 family protein -
  ST64987_RS01000 (ST64987_0150) mecA 170012..170761 (+) 750 WP_065972842.1 adaptor protein MecA Regulator
  ST64987_RS01005 (ST64987_0151) - 170765..171922 (+) 1158 WP_167401408.1 glycosyltransferase family 4 protein -
  ST64987_RS01010 (ST64987_0152) sufC 172083..172853 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  ST64987_RS01015 (ST64987_0153) sufD 172890..174152 (+) 1263 WP_011680669.1 Fe-S cluster assembly protein SufD -
  ST64987_RS01020 (ST64987_0154) - 174206..175438 (+) 1233 WP_167401409.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29167.69 Da        Isoelectric Point: 4.0481

>NTDB_id=371869 ST64987_RS01000 WP_065972842.1 170012..170761(+) (mecA) [Streptococcus thermophilus strain ST64987]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=371869 ST64987_RS01000 WP_065972842.1 170012..170761(+) (mecA) [Streptococcus thermophilus strain ST64987]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

99.197

100

0.992
  mecA Streptococcus thermophilus LMG 18311

99.197

100

0.992
  mecA Streptococcus mutans UA159

57.787

97.992

0.566
  mecA Streptococcus pneumoniae Rx1

46.586

100

0.466
  mecA Streptococcus pneumoniae D39

46.586

100

0.466
  mecA Streptococcus pneumoniae R6

46.586

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.586

100

0.466

Multiple sequence alignment