Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AbD4_RS16245 Genome accession   NZ_CP048849
Coordinates   3414883..3415557 (-) Length   224 a.a.
NCBI ID   WP_000161505.1    Uniprot ID   A0A0D5YFC9
Organism   Acinetobacter baumannii strain D4     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3409883..3420557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AbD4_RS16225 (AbD4_03271) - 3410295..3411179 (+) 885 WP_000144732.1 LysR family transcriptional regulator -
  AbD4_RS16230 (AbD4_03272) - 3411484..3412671 (+) 1188 WP_002010839.1 ammonium transporter -
  AbD4_RS16235 (AbD4_03273) - 3412824..3413522 (+) 699 WP_000184466.1 phosphatase PAP2 family protein -
  AbD4_RS16240 (AbD4_03274) - 3413523..3414857 (-) 1335 WP_000559381.1 two-component system sensor histidine kinase PmrB -
  AbD4_RS16245 (AbD4_03275) ciaR 3414883..3415557 (-) 675 WP_000161505.1 response regulator transcription factor Regulator
  AbD4_RS16250 (AbD4_03276) - 3415572..3417101 (-) 1530 Protein_3200 phosphoethanolamine transferase -
  AbD4_RS16255 (AbD4_03277) - 3417190..3417573 (+) 384 WP_001055589.1 transposase -
  AbD4_RS16260 (AbD4_03278) tnpB 3417570..3417905 (+) 336 WP_000619347.1 IS66 family insertion sequence element accessory protein TnpB -
  AbD4_RS16265 (AbD4_03279) - 3417980..3419563 (+) 1584 WP_001094424.1 IS66-like element ISAba25 family transposase -
  AbD4_RS20895 (AbD4_03280) - 3419595..3419720 (-) 126 Protein_3204 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25548.47 Da        Isoelectric Point: 5.3246

>NTDB_id=371011 AbD4_RS16245 WP_000161505.1 3414883..3415557(-) (ciaR) [Acinetobacter baumannii strain D4]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=371011 AbD4_RS16245 WP_000161505.1 3414883..3415557(-) (ciaR) [Acinetobacter baumannii strain D4]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTAAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAGTTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGTGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGCCAACGCATTGATTTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATCCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 9OF3
  PDB 9OF4
  PDB 9OF5
  PDB 9OF6
  PDB 9OF7
  PDB 9OF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.965

100

0.366

Multiple sequence alignment