Detailed information NTG0370915

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: C8250_RS24505
• Genome accession: NZ_CP048835
• Coordinates: 5429153..5430277 (-)
• Length: 374 a.a.
• NCBI ID: WP_138354131.1
• Uniprot ID: A0ABW8CIC5
• Organism: Streptomyces sp. So13.3
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5424153..5435277

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C8250_RS24480 (C8250_024495)	cseB	5425108..5425791 (-)	684	WP_138354127.1	two-component system response regulator CseB	-
C8250_RS24485 (C8250_024500)	-	5425784..5426392 (-)	609	WP_244809340.1	hypothetical protein	-
C8250_RS24490 (C8250_024505)	-	5426380..5426910 (-)	531	WP_138354128.1	SigE family RNA polymerase sigma factor	-
C8250_RS24495 (C8250_024510)	-	5427089..5427985 (-)	897	WP_138354129.1	A/G-specific adenine glycosylase	-
C8250_RS24500 (C8250_024515)	-	5428117..5428938 (+)	822	WP_138354130.1	hypothetical protein	-
C8250_RS24505 (C8250_024520)	disA	5429153..5430277 (-)	1125	WP_138354131.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
C8250_RS24510 (C8250_024525)	radA/sms	5430379..5431764 (-)	1386	WP_138354132.1	DNA repair protein RadA	Machinery gene
C8250_RS24515 (C8250_024530)	-	5431957..5433588 (+)	1632	WP_138354133.1	sigma-70 family RNA polymerase sigma factor	-
C8250_RS24520 (C8250_024535)	-	5433787..5434596 (-)	810	WP_138354156.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40394.22 Da
• Isoelectric Point: 5.0092

>NTDB_id=370915 C8250_RS24505 WP_138354131.1 5429153..5430277(-) (disA) [Streptomyces sp. So13.3]
MAANDRAAAPGKSGGSSAADALMRASLSAVAPGTGLRDGLERILRGNTGGLLVLGMDKTVESLCTGGFVLDVEFTATRLR
ELCKLDGALILDKDLTKILRAGVQLVPDSNIPTEETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVSQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRNRTVPEALVELDALPHAELLELTTVARALGYTGSPETLDSAVSPRGYRLLAKVPRLPNT
VIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=370915 C8250_RS24505 WP_138354131.1 5429153..5430277(-) (disA) [Streptomyces sp. So13.3]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGTTCCGCTGCTGATGCCCTGATGCGCGCCTCGCT
CAGCGCGGTCGCTCCCGGCACCGGCCTGCGTGACGGACTCGAACGCATTCTGCGGGGCAATACGGGCGGTCTGCTCGTCC
TCGGCATGGACAAGACCGTCGAGTCGCTCTGTACCGGCGGCTTCGTCCTCGACGTCGAATTCACCGCGACCCGGCTCCGC
GAACTGTGCAAGCTCGACGGCGCGCTGATCCTCGACAAGGACCTCACGAAGATTCTGCGGGCCGGTGTGCAGTTGGTCCC
CGACTCCAACATCCCGACCGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTGAGCAAGCAGGTCAACTTCCCGG
TCGTCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTGTACGTCGACGGGCAGCGCCGGGTCCTGGAGGACTCCGCCGCG
ATCCTGTCGCGGGCGAACCAGGCGCTGGCCACTCTGGAGCGCTACAAGCTGCGCCTGGACGAGGTGGCGGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTCAGCGCGGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGCTGGGCACCGACGGCCGGCTGCTCTCCCTGCAGCTGGACGAGCTGATCGCG
GGCGTCGAGCCGGAGCGCGAGCTGGTCGTCAGGGACTACGTGCCGGAGCCGACCGCGAAGCGGAACAGGACCGTGCCGGA
GGCGCTCGTCGAACTGGACGCGCTGCCGCACGCCGAGCTCCTCGAACTGACCACCGTGGCCCGTGCCCTGGGCTACACCG
GCTCCCCCGAGACGCTGGACTCCGCGGTCTCGCCGCGCGGCTACCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGAACACG
GTCATCGAGCGGCTGGTCGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCTGCGAGCGTCGACGACCTGCAGACGGTGGA
CGGGGTCGGCGAGGCGCGGGCGCGTTCGGTGCGGGAGGGCCTGTCCAGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (323-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.028	96.791	0.436