Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QE11421_RS05105 Genome accession   NZ_CP048821
Coordinates   1025845..1026501 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain QEC11-421     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1020845..1031501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QE11421_RS05075 (QE11421_4930) yecA 1022096..1022761 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  QE11421_RS05095 (QE11421_4935) pgsA 1023411..1023959 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QE11421_RS05100 (QE11421_4940) uvrC 1024016..1025848 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QE11421_RS05105 (QE11421_4945) letA 1025845..1026501 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QE11421_RS25525 - 1026643..1026714 (+) 72 Protein_1015 transcriptional regulator -
  QE11421_RS05110 yecU 1026797..1026973 (+) 177 WP_000590347.1 protein YecU -
  QE11421_RS05115 (QE11421_4950) yecF 1026960..1027184 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QE11421_RS05120 (QE11421_4955) sdiA 1027251..1027973 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  QE11421_RS05125 (QE11421_4960) tcyN 1028203..1028955 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QE11421_RS05130 (QE11421_4965) tcyL 1028952..1029620 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QE11421_RS05135 (QE11421_4970) dcyD 1029635..1030621 (-) 987 WP_001128238.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=370723 QE11421_RS05105 WP_000611335.1 1025845..1026501(-) (letA) [Escherichia coli strain QEC11-421]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=370723 QE11421_RS05105 WP_000611335.1 1025845..1026501(-) (letA) [Escherichia coli strain QEC11-421]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486