Detailed information NTG0370107

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GCO85_RS09435
• Genome accession: NZ_CP048618
• Coordinates: 2096540..2097814 (-)
• Length: 424 a.a.
• NCBI ID: WP_011215825.1
• Uniprot ID: Q5WVJ1
• Organism: Legionella pneumophila strain ERS1305867
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2091540..2102814

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCO85_RS09425 (GCO85_09435)	-	2093449..2093727 (-)	279	WP_011214112.1	HU family DNA-binding protein	-
GCO85_RS09430 (GCO85_09440)	lon	2093856..2096270 (-)	2415	WP_304607884.1	endopeptidase La	-
GCO85_RS09435 (GCO85_09445)	clpX	2096540..2097814 (-)	1275	WP_011215825.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
GCO85_RS09440 (GCO85_09450)	clpP	2097955..2098599 (-)	645	WP_014844185.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
GCO85_RS09445 (GCO85_09455)	tig	2098602..2099933 (-)	1332	WP_014844186.1	trigger factor	-
GCO85_RS09470 (GCO85_09480)	-	2100802..2102028 (+)	1227	WP_014844187.1	site-specific integrase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46641.21 Da
• Isoelectric Point: 5.0727

>NTDB_id=370107 GCO85_RS09435 WP_011215825.1 2096540..2097814(-) (clpX) [Legionella pneumophila strain ERS1305867]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=370107 GCO85_RS09435 WP_011215825.1 2096540..2097814(-) (clpX) [Legionella pneumophila strain ERS1305867]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTATGTAATGATATTATTCGAGAAGAAACACATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
ACTCGGTAAAAGTAATATACTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGTGAAGACGTTGAAAATATCATC
CAGAAGTTATTACAGAAGTGTGACTATGACGTAGATAAGGCGCAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCCGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAAGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCGAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGACGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTAATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCGAAAAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGACGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACCATGTATGACTTACCTTCCTTGGAAGGTGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5WVJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526