Detailed information NTG0369777

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: FIM06_RS17380
• Genome accession: NZ_CP041144
• Coordinates: 3456799..3457962 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UCMB5044
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3451799..3462962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIM06_RS17350 (FIM06_3241)	-	3452063..3452482 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
FIM06_RS17355 (FIM06_3242)	comFC	3452557..3453246 (-)	690	WP_199791910.1	phosphoribosyltransferase family protein	Machinery gene
FIM06_RS17360 (FIM06_3243)	-	3453252..3453536 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
FIM06_RS17365 (FIM06_3244)	comFA	3453594..3454979 (-)	1386	WP_105937245.1	DEAD/DEAH box helicase	Machinery gene
FIM06_RS17370 (FIM06_3245)	-	3455087..3455935 (-)	849	WP_105937244.1	DegV family protein	-
FIM06_RS17375 (FIM06_3246)	degU	3456033..3456722 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
FIM06_RS17380 (FIM06_3247)	degS	3456799..3457962 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
FIM06_RS17385 (FIM06_3248)	-	3458185..3458832 (+)	648	WP_007614107.1	YigZ family protein	-
FIM06_RS17390 (FIM06_3249)	-	3458837..3460057 (+)	1221	WP_105937243.1	LCP family protein	-
FIM06_RS17395 (FIM06_3250)	-	3460156..3461232 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
FIM06_RS17400 (FIM06_3251)	-	3461365..3462561 (-)	1197	WP_105937242.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=369777 FIM06_RS17380 WP_007407484.1 3456799..3457962(-) (degS) [Bacillus velezensis strain UCMB5044]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=369777 FIM06_RS17380 WP_007407484.1 3456799..3457962(-) (degS) [Bacillus velezensis strain UCMB5044]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTAGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAAAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTGGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951